Table 6.

Antiviral therapy in 38 HCV infected childhood cancer survivors


Treatment

No. patients

Responders

Nonresponders

On therapy
IFN   20   6   14*  0  
IFN + ribavirin  16   7   9  0  
   Primary therapy   12   5   7   0  
   Secondary therapy   4   2   2   0  
PEG-IFN + ribavirin  11   4   2  5  
   Primary therapy   6   3   0   3  
   Secondary therapy
 
5
 
1
 
2
 
2
 

Treatment

No. patients

Responders

Nonresponders

On therapy
IFN   20   6   14*  0  
IFN + ribavirin  16   7   9  0  
   Primary therapy   12   5   7   0  
   Secondary therapy   4   2   2   0  
PEG-IFN + ribavirin  11   4   2  5  
   Primary therapy   6   3   0   3  
   Secondary therapy
 
5
 
1
 
2
 
2
 

Abbreviations: IFN, interferon; PEG-IFN, pegylated interferon.

*

Includes 2 patients unable to complete therapy because of psychosis (1) or depression (1)

Includes 2 patients unable to complete therapy due to severe anemia (1) and hypothyroidism (1)

Includes 1 patient unable to complete therapy due to depression; this patient was also taken off interferon for the same reason

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