Amount of long-term bone loss after allogeneic stem cell transplantation and its correlating factors
. | Spine . | Total body . | Femoral neck . | Ward triangle . |
|---|---|---|---|---|
| Bone loss (percent/year ± SD) | 0.62 ± 2.23* | 0.4 ± 1.18* | 2.27 ± 3.0* | 3.47 ± 3.41* |
| Prednisolone dose | † | † | † | † |
| Cumulative steroid total (20.3 ± 15.3 g*) | 0.43∥ | 0.48∥ | 0.39§ | 0.28‡ |
| Cum steroid per day (13.5 ± 10.8 mg/day*) | 0.43∥ | 0.49∥ | 0.41§ | 0.3‡ |
| Exposure to CyA (52% ± 34% of days*) | 0.2 NS | 0.23‡ | 0.01 NS | 0.09 NS |
| Loss of body weight (1.2% ± 2.7%/year*) | 0.26‡ | 0.47∥ | 0.13 NS | 0.07 NS |
| Loss of muscle mass (2.1% ± 2%/year*) | 0.39§ | 0.54∥ | 0.2 NS | 0.12 NS |
| Z-score baseline | 0.22‡ | 0.23‡ | 0.36‡ | 0.24‡ |
. | Spine . | Total body . | Femoral neck . | Ward triangle . |
|---|---|---|---|---|
| Bone loss (percent/year ± SD) | 0.62 ± 2.23* | 0.4 ± 1.18* | 2.27 ± 3.0* | 3.47 ± 3.41* |
| Prednisolone dose | † | † | † | † |
| Cumulative steroid total (20.3 ± 15.3 g*) | 0.43∥ | 0.48∥ | 0.39§ | 0.28‡ |
| Cum steroid per day (13.5 ± 10.8 mg/day*) | 0.43∥ | 0.49∥ | 0.41§ | 0.3‡ |
| Exposure to CyA (52% ± 34% of days*) | 0.2 NS | 0.23‡ | 0.01 NS | 0.09 NS |
| Loss of body weight (1.2% ± 2.7%/year*) | 0.26‡ | 0.47∥ | 0.13 NS | 0.07 NS |
| Loss of muscle mass (2.1% ± 2%/year*) | 0.39§ | 0.54∥ | 0.2 NS | 0.12 NS |
| Z-score baseline | 0.22‡ | 0.23‡ | 0.36‡ | 0.24‡ |
P values classified as ns = not significant, ‡P < .05, §P < .001, ∥P ≤ .0001.
CyA indicates cyclosporin A; NS, not significant; Z-score correlation given for the corresponding site of measurement.
The mean ± 1 standard deviation of the corresponding parameter.
The correlation coefficients and the P values.