Patient characteristics
. | No. patients . | . | . | |
|---|---|---|---|---|
| Parameter . | RICE (n = 36) . | ICE historical controls (n = 147) . | P . | |
| Age, y | .10 | |||
| 60 and younger | 28 | 129 | ||
| Older than 60 | 8 | 18 | ||
| Median (range) | 45 (23-72) | 48 (18-68) | ||
| Previous chemotherapy | ||||
| CHOP | 16 | 65 | ||
| CHOP-like | 2 | 31 | ||
| NHL-1521 | 16 | 50 | ||
| ABVD | 2 | 0 | ||
| Stanford-V | 0 | 1 | ||
| Disease status | .35 | |||
| Relapsed | 23 | 80 | ||
| Primary refractory | 13 | 67 | ||
| Karnofsky performance status | .23 | |||
| 80 or greater | 28 | 97 | ||
| Less than 80 | 8 | 50 | ||
| LDH level | .45 | |||
| Elevated | 18 | 61 | ||
| Normal | 18 | 86 | ||
| Stage at protocol entry | .38 | |||
| I or II | 10 | 31 | ||
| III or IV | 26 | 116 | ||
| Second-line age-adjusted IPI | .19 | |||
| Low/low-intermediate | 19 | 59 | ||
| High-intermediate/high | 17 | 88 | ||
. | No. patients . | . | . | |
|---|---|---|---|---|
| Parameter . | RICE (n = 36) . | ICE historical controls (n = 147) . | P . | |
| Age, y | .10 | |||
| 60 and younger | 28 | 129 | ||
| Older than 60 | 8 | 18 | ||
| Median (range) | 45 (23-72) | 48 (18-68) | ||
| Previous chemotherapy | ||||
| CHOP | 16 | 65 | ||
| CHOP-like | 2 | 31 | ||
| NHL-1521 | 16 | 50 | ||
| ABVD | 2 | 0 | ||
| Stanford-V | 0 | 1 | ||
| Disease status | .35 | |||
| Relapsed | 23 | 80 | ||
| Primary refractory | 13 | 67 | ||
| Karnofsky performance status | .23 | |||
| 80 or greater | 28 | 97 | ||
| Less than 80 | 8 | 50 | ||
| LDH level | .45 | |||
| Elevated | 18 | 61 | ||
| Normal | 18 | 86 | ||
| Stage at protocol entry | .38 | |||
| I or II | 10 | 31 | ||
| III or IV | 26 | 116 | ||
| Second-line age-adjusted IPI | .19 | |||
| Low/low-intermediate | 19 | 59 | ||
| High-intermediate/high | 17 | 88 | ||