Table 1.

Patient characteristics



No. patients

Parameter
RICE (n = 36)
ICE historical controls (n = 147)
P
Age, y    .10  
    60 and younger   28   129   
    Older than 60   8   18   
    Median (range)   45 (23-72)   48 (18-68)   
Previous chemotherapy    
    CHOP   16   65   
    CHOP-like   2   31   
    NHL-1521   16   50   
    ABVD   2   0   
    Stanford-V   0   1   
Disease status    .35  
    Relapsed   23   80   
    Primary refractory   13   67   
Karnofsky performance status    .23  
    80 or greater   28   97   
    Less than 80   8   50   
LDH level    .45  
    Elevated   18   61   
    Normal   18   86   
Stage at protocol entry    .38  
    I or II   10   31   
    III or IV   26   116   
Second-line age-adjusted IPI    .19  
    Low/low-intermediate   19   59   
    High-intermediate/high
 
17
 
88
 

 


No. patients

Parameter
RICE (n = 36)
ICE historical controls (n = 147)
P
Age, y    .10  
    60 and younger   28   129   
    Older than 60   8   18   
    Median (range)   45 (23-72)   48 (18-68)   
Previous chemotherapy    
    CHOP   16   65   
    CHOP-like   2   31   
    NHL-1521   16   50   
    ABVD   2   0   
    Stanford-V   0   1   
Disease status    .35  
    Relapsed   23   80   
    Primary refractory   13   67   
Karnofsky performance status    .23  
    80 or greater   28   97   
    Less than 80   8   50   
LDH level    .45  
    Elevated   18   61   
    Normal   18   86   
Stage at protocol entry    .38  
    I or II   10   31   
    III or IV   26   116   
Second-line age-adjusted IPI    .19  
    Low/low-intermediate   19   59   
    High-intermediate/high
 
17
 
88
 

 
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