Characteristics of T-ALL patients
. | Gene expression profile set (n = 33) . | RT quantitative PCR set (n = 18) . |
|---|---|---|
| Clinical characteristics | ||
| Male/Female | 24/9 | 14/4 |
| Age, y (range) | 29.5 (14-52) | 22.5 (14-37) |
| WBC × 109/L (range) | 87 (3-700) | 52 (6.8-848) |
| Immunophenotypic characteristics | ||
| T1 | 2 | 0 |
| T2 | 15 | 7 |
| T3 | 10 | 7 |
| T4 | 2 | 1 |
| Incomplete phenotype | 4 | 3 |
| Cytogenetic characteristics | ||
| Normal karyotype | 8 | 8 |
| Not evaluable | 13 | 8 |
| t(4; 11)* | 1 | 0 |
| t(10; 14) | 1 | 0 |
| del(6q) | 2 | 1 |
| del(7q) | 1 | 0 |
| Other simple alterations: | 4† | 1‡ |
| Other complex alterations: | 3§ | 0 |
. | Gene expression profile set (n = 33) . | RT quantitative PCR set (n = 18) . |
|---|---|---|
| Clinical characteristics | ||
| Male/Female | 24/9 | 14/4 |
| Age, y (range) | 29.5 (14-52) | 22.5 (14-37) |
| WBC × 109/L (range) | 87 (3-700) | 52 (6.8-848) |
| Immunophenotypic characteristics | ||
| T1 | 2 | 0 |
| T2 | 15 | 7 |
| T3 | 10 | 7 |
| T4 | 2 | 1 |
| Incomplete phenotype | 4 | 3 |
| Cytogenetic characteristics | ||
| Normal karyotype | 8 | 8 |
| Not evaluable | 13 | 8 |
| t(4; 11)* | 1 | 0 |
| t(10; 14) | 1 | 0 |
| del(6q) | 2 | 1 |
| del(7q) | 1 | 0 |
| Other simple alterations: | 4† | 1‡ |
| Other complex alterations: | 3§ | 0 |
t(4; 11) (q21;p15). Molecular studies detected the presence of NUP/RAP molecular rearrangement.
dupl(12) (q12;q24); add(19) (p13); del(11q) (q21); del(4) (p14).
del(3), del(17).
del(2)(p16), add(7)(p22), + 22; del(7)(p15), t(9; 12)(q12;q32), del(13)(q13;q33); der(1;13)(q10;q12), +1, +4, +18+21, +22.