Characteristics of patients and controls
. | Median (range or percentage) . | . | . | ||
|---|---|---|---|---|---|
. | Patients, n = 63 . | Controls, n = 63 . | All, n = 126 . | ||
| Time from diagnosis to presentation to Mayo, mo | 1.5 (0-71.6) | 1.4 (0-11.0) | 1.4 (0-71.6) | ||
| Diagnosis to transplantation/treatment, mo | 4.4 (1.3-74.6)* | 1.4 (0-13.2) | 2.7 (0-74.6) | ||
| No. of males | 36 (57%) | 36 (57%) | 72 (57%) | ||
| Age, y | 53 (30-69) | 53 (32-69) | 53 (30-69) | ||
| No. with nerve involvement | 11 (17%) | 11 (17%) | 22 (17%) | ||
| Left ventricular ejection fraction | 65% (30%-79%) | 65% (30%-80%) | 65% (7%-80%) | ||
| No. with left ventricular ejection fraction less than or equal to 50% | 4 (6%)* | 12 (19%) | 16 (13%) | ||
| Interventricular septum, mm | 12 (7-23) | 12 (7-25) | 12 (7-25) | ||
| No. with interventricular septum greater than 15 mm | 11 (17%) | 10 (16%) | 21 (17%) | ||
| Serum alkaline phosphatase level, U/L | 196 (57-1195) | 196 (76-1926) | 196 (57-1926) | ||
| No. with serum alkaline phosphatase level greater than twice normal | 8 (13%) | 4 (6%) | 12 (10%) | ||
| Serum creatinine level, mg/dL | 1.1 (0.5-2.1) | 1.0 (0.6-10.3) | 1.0 (0.5-10.3) | ||
| Serum M protein level, g/dL | 0.5 (0.0-2.9) | 0.0 (0.0-2.8) | 0.0 (0.0-2.9) | ||
| Serum albumin level, g/dL | 2.7 (1.4-3.8) | 2.7 (0.9-4.1) | 2.7 (0.9-4.1) | ||
| 24-h urine protein level, g/24 h | 4.6 (0.0-20.7) | 5.3 (0.1-24.7) | 4.8 (0.0-24.7) | ||
| No. with 24-h urine protein level greater than 3 g/24 h | 37 (59%) | 37 (59%) | 74 (59%) | ||
| 24-h urine M protein level | 0.1 (0.0-3.1) | 0.2 (0.0-4.0) | 0.2 (0.0-4.0) | ||
| Bone marrow plasma cells | 10% (1%-91%) | 8% (1%-66%) | 8% (1.0%-91%) | ||
| No. with bone marrow plasma cells greater than 30% | 8 (16%) | 3 (5%) | 11 (10%) | ||
. | Median (range or percentage) . | . | . | ||
|---|---|---|---|---|---|
. | Patients, n = 63 . | Controls, n = 63 . | All, n = 126 . | ||
| Time from diagnosis to presentation to Mayo, mo | 1.5 (0-71.6) | 1.4 (0-11.0) | 1.4 (0-71.6) | ||
| Diagnosis to transplantation/treatment, mo | 4.4 (1.3-74.6)* | 1.4 (0-13.2) | 2.7 (0-74.6) | ||
| No. of males | 36 (57%) | 36 (57%) | 72 (57%) | ||
| Age, y | 53 (30-69) | 53 (32-69) | 53 (30-69) | ||
| No. with nerve involvement | 11 (17%) | 11 (17%) | 22 (17%) | ||
| Left ventricular ejection fraction | 65% (30%-79%) | 65% (30%-80%) | 65% (7%-80%) | ||
| No. with left ventricular ejection fraction less than or equal to 50% | 4 (6%)* | 12 (19%) | 16 (13%) | ||
| Interventricular septum, mm | 12 (7-23) | 12 (7-25) | 12 (7-25) | ||
| No. with interventricular septum greater than 15 mm | 11 (17%) | 10 (16%) | 21 (17%) | ||
| Serum alkaline phosphatase level, U/L | 196 (57-1195) | 196 (76-1926) | 196 (57-1926) | ||
| No. with serum alkaline phosphatase level greater than twice normal | 8 (13%) | 4 (6%) | 12 (10%) | ||
| Serum creatinine level, mg/dL | 1.1 (0.5-2.1) | 1.0 (0.6-10.3) | 1.0 (0.5-10.3) | ||
| Serum M protein level, g/dL | 0.5 (0.0-2.9) | 0.0 (0.0-2.8) | 0.0 (0.0-2.9) | ||
| Serum albumin level, g/dL | 2.7 (1.4-3.8) | 2.7 (0.9-4.1) | 2.7 (0.9-4.1) | ||
| 24-h urine protein level, g/24 h | 4.6 (0.0-20.7) | 5.3 (0.1-24.7) | 4.8 (0.0-24.7) | ||
| No. with 24-h urine protein level greater than 3 g/24 h | 37 (59%) | 37 (59%) | 74 (59%) | ||
| 24-h urine M protein level | 0.1 (0.0-3.1) | 0.2 (0.0-4.0) | 0.2 (0.0-4.0) | ||
| Bone marrow plasma cells | 10% (1%-91%) | 8% (1%-66%) | 8% (1.0%-91%) | ||
| No. with bone marrow plasma cells greater than 30% | 8 (16%) | 3 (5%) | 11 (10%) | ||
P < .05.