Stratification of the included patients with one unexplained pregnancy loss from the 10th week of amenorrhea, according to the principal underlying thrombophilic disorders, and effect of the two treatments on the rate of live births
Main thrombophilic disorder . | With negative protein Z deficiency and negative antiprotein Z antibodies . | With positive protein Z deficiency and negative antiprotein Z antibodies . | With negative protein Z deficiency and positive antiprotein Z antibodies . | With positive protein Z deficiency and positive antiprotein Z antibodies . |
---|---|---|---|---|
Factor V Leiden mutation | 26 | 16 | 20 | 10 |
Low-dose aspirin | 06/13 | 02/08 | 03/10 | 01/05 |
Enoxaparin | 13/13 | 08/08 | 10/10 | 03/05 |
Prothrombin G20210A mutation | 30 | 10 | 14 | 06 |
Low-dose aspirin | 07/15 | 01/05 | 02/07 | 00/03 |
Enoxaparin | 14/15 | 04/05 | 05/07 | 01/03 |
Protein S deficiency | 04 | 12 | 08 | 04 |
Low-dose aspirin | 01/02 | 00/06 | 00/04 | 00/02 |
Enoxaparin | 02/02 | 06/06 | 03/04 | 00/02 |
Patients: total | 60 | 38 | 42 | 20 |
Low-dose aspirin | 14/30 | 03/19 | 05/21 | 01/10 |
Enoxaparin | 29/30 | 18/19 | 18/21 | 04/10 |
Main thrombophilic disorder . | With negative protein Z deficiency and negative antiprotein Z antibodies . | With positive protein Z deficiency and negative antiprotein Z antibodies . | With negative protein Z deficiency and positive antiprotein Z antibodies . | With positive protein Z deficiency and positive antiprotein Z antibodies . |
---|---|---|---|---|
Factor V Leiden mutation | 26 | 16 | 20 | 10 |
Low-dose aspirin | 06/13 | 02/08 | 03/10 | 01/05 |
Enoxaparin | 13/13 | 08/08 | 10/10 | 03/05 |
Prothrombin G20210A mutation | 30 | 10 | 14 | 06 |
Low-dose aspirin | 07/15 | 01/05 | 02/07 | 00/03 |
Enoxaparin | 14/15 | 04/05 | 05/07 | 01/03 |
Protein S deficiency | 04 | 12 | 08 | 04 |
Low-dose aspirin | 01/02 | 00/06 | 00/04 | 00/02 |
Enoxaparin | 02/02 | 06/06 | 03/04 | 00/02 |
Patients: total | 60 | 38 | 42 | 20 |
Low-dose aspirin | 14/30 | 03/19 | 05/21 | 01/10 |
Enoxaparin | 29/30 | 18/19 | 18/21 | 04/10 |