Differences among BM and MPB CD34+ cells generated after “continuous” LTC
. | . | Week . | . | . | ||
|---|---|---|---|---|---|---|
. | Input . | 1 . | 3 . | 4 . | ||
| BM | ||||||
| Telomere length on CD34+ cells by flow-FISH, kb | 6.8 | 6.8 | 6.5 | ND | ||
| Secondary engraftment | − | + | + | − | ||
| MPB | ||||||
| Telomere length on CD34+ cells by flow-FISH, kb | 7.2 | 7.4 | 7.1 | ND | ||
| Telomerase activity on CD34+ cells, TPG units | 10.2 | 13.5 | 11.9 | ND | ||
| Telomere length on stem/progenitor-enriched fraction by flow-FISH, kb* | 7.2 | 7.6 | 7.1 | 6.5 | ||
| Secondary engraftment | − | + | + | − | ||
. | . | Week . | . | . | ||
|---|---|---|---|---|---|---|
. | Input . | 1 . | 3 . | 4 . | ||
| BM | ||||||
| Telomere length on CD34+ cells by flow-FISH, kb | 6.8 | 6.8 | 6.5 | ND | ||
| Secondary engraftment | − | + | + | − | ||
| MPB | ||||||
| Telomere length on CD34+ cells by flow-FISH, kb | 7.2 | 7.4 | 7.1 | ND | ||
| Telomerase activity on CD34+ cells, TPG units | 10.2 | 13.5 | 11.9 | ND | ||
| Telomere length on stem/progenitor-enriched fraction by flow-FISH, kb* | 7.2 | 7.6 | 7.1 | 6.5 | ||
| Secondary engraftment | − | + | + | − | ||
ND indicates not done due to the insufficient CD34+ cell recovery.
Mean of 2 different experiments.