Comparison of clonality in BAL fluid and diagnostic biopsy in 18 patients
. | Clonal BAL fluid . | Nonclonal BAL fluid . |
|---|---|---|
| Clonal biopsy | 6 primary pulmonary B-NHLs; 2 secondary B-NHLs | 1 primary pulmonary B-NHL* ; 1 bronchiolitis obliterans organizing pneumoniae |
| Nonclonal biopsy | 1 vasculitis | 1 primary pulmonary lymphoma; 6 nonlymphomatous samples† |
. | Clonal BAL fluid . | Nonclonal BAL fluid . |
|---|---|---|
| Clonal biopsy | 6 primary pulmonary B-NHLs; 2 secondary B-NHLs | 1 primary pulmonary B-NHL* ; 1 bronchiolitis obliterans organizing pneumoniae |
| Nonclonal biopsy | 1 vasculitis | 1 primary pulmonary lymphoma; 6 nonlymphomatous samples† |
The BAL fluid lymphocytes were oligoclonal. Despite the fact that a peak with an identical size to the “tumoral” peak was seen in the oligoclonality, it was not possible to assume that the tumoral clone was present in the BAL fluid.
Pulmonary fibrosis (n = 1), drug-related pneumoniae (n=1), bronchiolitis obliterans organizing pneumonia (n=1), granulomatosis (n=2), viral infection (n = 1).