CDR3 nucleotide sequences of dominant peaks
. | . | CDR3 Sequences . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient no. . | . | VH . | . | n1 . | DH . | n2 . | JH . | . | ||||||
| 1 | BAL | VH3 - 23 | TGTGCGAAAG | CCTTGCGGC | GGATTACGATTTTTGGAGTGGGTAT | CGGGAAGGATGGGGG | CTTTGAGTACTGG | JH4 | ||||||
| Tumor | VH3 - 23 | TGTGCGAAAG | CCTTGCGGC | GGATTACGATTTTTGGAGTGGGTAT | CGGGAAGGATGGGGG | CTTTGAGTACTGG | JH4 | |||||||
| 2 | BAL | VH3 - 23 | TGTGCGAAA | TTGGTG | GGAGGCAGCTGCT | CTCTCCCG | TGTGAATACTGG | JH4 | ||||||
| Tumor | VH3 - 23 | TGTGCGAAA | TTGGTG | GGAGGCAGCTGCT | CTCTCCCG | TGTGAATACTGG | JH4 | |||||||
| 3 | BAL | VH* | TGTGCGAGAGA | CTTCTCGGGTCCTCCA | AGTGGGAGCTAC | C | TCTACTACTGG | JH4 | ||||||
| Tumor | VH* | TGTGCGAGAGA | CTTCTCGGGTCCTCCA | AGTGGGAGCTAC | C | TCTACTACTGG | JH4 | |||||||
| 4 | BAL | VH3 - 15 | TGTACCACAGA | TCCGCTTG | ATTACGATTTTTGGAGTGG | CGGT | TACTACAACTCCATGGACGTCTGG | JH6 | ||||||
| Tumor | VH3 - 15 | TGTACCACAGA | TCCGCTTG | ATTACGATTTTTGGAGTGG | CGGT | TACTACAACTCCATGGACGTCTGG | JH6 | |||||||
| 5 | BAL | VH3 - 30 | TGTGCGAGAGA | AGGATATTTTGACTGGTTATT | TGCGCAACTCTTTGGCCCA | TTTGACTGCTGG | JH4 | |||||||
| Tumor | VH3 - 30 | TGTGCGAGAGA | AGGATATTTTGACTGGTTATT | TGCGCAACTCTTTGGCCCA | TTTGACTGCTGG | JH4 | ||||||||
| 6 | BAL | VH* | TGTGCGAGAGA | T | CATCTGCGGGGAC | G | TGTCTTTGATGTCTGG | JH3 | ||||||
| Tumor | VH* | TGTGCGAGAGA | T | CATCTGCGGGGAC | G | TGTCTTTGATGTCTGG | JH3 | |||||||
| 7 | BAL | VH3 - 7 | TGTGCGAGA | GGAA | TTCGGAGTGATGA | CGGTCTTAGTGGAGGGGCAA | TGGACGTCTGG | JH3 | ||||||
| 8 | BAL | VH5 - 51 | TGTGCGAGA | ACGA | AATACGGTTACAACTC | GG | ACGGTATGGACGTCTGG | JH6 | ||||||
| 9 | BAL | VH5 - a03 | TGTGCGAGA | GTGGTACCAGCTGATAT | AGTCGGGAT | CTACTACTACGCTTTGGACGTCTGG | JH6 | |||||||
| 10 | BAL | VH3 - 13 | TGTGCAAGAG | GA | TATTACTATGCTTCGGGGAGTT | TGG | TTGACTACTGG | JH4 | ||||||
. | . | CDR3 Sequences . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient no. . | . | VH . | . | n1 . | DH . | n2 . | JH . | . | ||||||
| 1 | BAL | VH3 - 23 | TGTGCGAAAG | CCTTGCGGC | GGATTACGATTTTTGGAGTGGGTAT | CGGGAAGGATGGGGG | CTTTGAGTACTGG | JH4 | ||||||
| Tumor | VH3 - 23 | TGTGCGAAAG | CCTTGCGGC | GGATTACGATTTTTGGAGTGGGTAT | CGGGAAGGATGGGGG | CTTTGAGTACTGG | JH4 | |||||||
| 2 | BAL | VH3 - 23 | TGTGCGAAA | TTGGTG | GGAGGCAGCTGCT | CTCTCCCG | TGTGAATACTGG | JH4 | ||||||
| Tumor | VH3 - 23 | TGTGCGAAA | TTGGTG | GGAGGCAGCTGCT | CTCTCCCG | TGTGAATACTGG | JH4 | |||||||
| 3 | BAL | VH* | TGTGCGAGAGA | CTTCTCGGGTCCTCCA | AGTGGGAGCTAC | C | TCTACTACTGG | JH4 | ||||||
| Tumor | VH* | TGTGCGAGAGA | CTTCTCGGGTCCTCCA | AGTGGGAGCTAC | C | TCTACTACTGG | JH4 | |||||||
| 4 | BAL | VH3 - 15 | TGTACCACAGA | TCCGCTTG | ATTACGATTTTTGGAGTGG | CGGT | TACTACAACTCCATGGACGTCTGG | JH6 | ||||||
| Tumor | VH3 - 15 | TGTACCACAGA | TCCGCTTG | ATTACGATTTTTGGAGTGG | CGGT | TACTACAACTCCATGGACGTCTGG | JH6 | |||||||
| 5 | BAL | VH3 - 30 | TGTGCGAGAGA | AGGATATTTTGACTGGTTATT | TGCGCAACTCTTTGGCCCA | TTTGACTGCTGG | JH4 | |||||||
| Tumor | VH3 - 30 | TGTGCGAGAGA | AGGATATTTTGACTGGTTATT | TGCGCAACTCTTTGGCCCA | TTTGACTGCTGG | JH4 | ||||||||
| 6 | BAL | VH* | TGTGCGAGAGA | T | CATCTGCGGGGAC | G | TGTCTTTGATGTCTGG | JH3 | ||||||
| Tumor | VH* | TGTGCGAGAGA | T | CATCTGCGGGGAC | G | TGTCTTTGATGTCTGG | JH3 | |||||||
| 7 | BAL | VH3 - 7 | TGTGCGAGA | GGAA | TTCGGAGTGATGA | CGGTCTTAGTGGAGGGGCAA | TGGACGTCTGG | JH3 | ||||||
| 8 | BAL | VH5 - 51 | TGTGCGAGA | ACGA | AATACGGTTACAACTC | GG | ACGGTATGGACGTCTGG | JH6 | ||||||
| 9 | BAL | VH5 - a03 | TGTGCGAGA | GTGGTACCAGCTGATAT | AGTCGGGAT | CTACTACTACGCTTTGGACGTCTGG | JH6 | |||||||
| 10 | BAL | VH3 - 13 | TGTGCAAGAG | GA | TATTACTATGCTTCGGGGAGTT | TGG | TTGACTACTGG | JH4 | ||||||
Underlined nucleotides are mutated when compared with the more homologous germline segment.
VH nucleotide sequence was too short for the assessment of the more homologous VH germline segment.