Table 2.

Allele frequency and genotype distribution of the IL-10−1082, IL-10−819, and IL-10−592 polymorphisms in 199 patients with DLBCL and 112 healthy control subjects

Control subjects
Patients with DLBCL
Allele frequency   
IL-10−1082G  0.39   0.47* 
IL-10−1082A  0.61   0.53  
IL-10−819C  0.68   0.745  
IL-10−819T  0.32   0.255  
IL-10−592C  0.68   0.745  
IL-10−592A  0.32   0.255  
Genotype distribution (%)   
IL-10−1082GG  20 (18)   44 (22)† 
IL-10−1082GA  47 (42)   100 (50)† 
IL-10−1082AA  45 (40)   55 (28)  
IL-10−819CC  53 (47)   107 (54)  
IL-10−819CT  46 (41)   81 (41)  
IL-10−819TT  13 (12)   11 (5)  
IL-10−592CC  53 (47)   107 (54)  
IL-10−592CA  46 (41)   81 (41)  
IL-10−592AA
 		 13 (12)
 		 11 (5)
 
Control subjects
Patients with DLBCL
Allele frequency   
IL-10−1082G  0.39   0.47* 
IL-10−1082A  0.61   0.53  
IL-10−819C  0.68   0.745  
IL-10−819T  0.32   0.255  
IL-10−592C  0.68   0.745  
IL-10−592A  0.32   0.255  
Genotype distribution (%)   
IL-10−1082GG  20 (18)   44 (22)† 
IL-10−1082GA  47 (42)   100 (50)† 
IL-10−1082AA  45 (40)   55 (28)  
IL-10−819CC  53 (47)   107 (54)  
IL-10−819CT  46 (41)   81 (41)  
IL-10−819TT  13 (12)   11 (5)  
IL-10−592CC  53 (47)   107 (54)  
IL-10−592CA  46 (41)   81 (41)  
IL-10−592AA
 		 13 (12)
 		 11 (5)
 
*

P = .043, frequency of the IL-10−1082G allele in patients with DLBCL as compared with control subjects. P value refers to the χ2 test.

†

P = .023, frequency of the IL-10−1082GG/GA genotypes in patients with DLBCL as compared with control subjects. P value refers to the χ2 test.

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