Clinical data of the patients after HSCT
Patient no./disease . | Age, y/sex . | Transplantation date, d/mo/y . | HSCT . | Conditioning . | GVHD . | Day after HSCT . | Other complications . |
|---|---|---|---|---|---|---|---|
| 1123/AML 1.R | 61/M | 19/06/03 | MUD PBSCT | FLAMSA | Y, grade II skin | +14 | None |
| 1124/AML refr. | 60/M | 05/09/03 | h-PBSC/BMT | FLAMSA | Y, grade II skin | +28 | Fever day −5/+6 |
| 1125/ALL Cr2 | 54/M | 11/09/03 | MUD PBSCT | FLAMSA | Y, grades I, II skin | +13 | Fever day −5/+1 |
| 1127/AML 1.R | 44/F | 15/11/03 | MUD PBSCT | FLAMSA | Y, grade II skin | +20 | None |
| 1128/AML 1.R | 36/M | 13/02/03 | h-PBSC/BMT | FLAMSA | N | NA | None |
| 1129/AML Cr1 | 50/F | 14/10/03 | SIB PBSCT | FLAMSA | N | NA | None |
| 1130/AML Cr1 | 56/M | 22/10/03 | MUD PBSCT | FLAMSA | N | NA | None |
| 1131/AML Cr1 | 58/F | 28/10/03 | SIB PBSC | FLAMSA | Y, grade II skin | +20 | None |
| 1132/AML-refr | 54/F | 29/10/03 | MUD PBSCT | FLAMSA | N | NA | Fever day −2/5 |
| 1133/AML 1.R | 34/M | 28/11/03 | h-PBSCT | FLAMSA | N | NA | Fever day 0 |
| 711/T-NHL | 22/F | 21/05/03 | MUD BMT | TBI 8 Gy FAra CY | Y, grade II skin | +75 | Fever |
| 712/AML MDS | 60/M | 14/07/03 | MUD PBSCT | FA-BCNUMel/RIT | Y, skin liver | +35 | None |
| 713/ALL/Cr1 | 26/M | 09/07/03 | MUD PBSCT | TBI-CY | Y, grade II intestine | +57 | None |
| 714/AML | 50/F | 07/07/03 | MUD PBSCT | FA-BCNUMel/RIT | Y, skin | +26 | None |
| 717/Foll. Ly | 46/M | 27/08/03 | MUD PBSCT | TBI 8 Gy FAra CY | Y, grade III skin | +19 | None |
| 720/AML | 49/F | 17/09/03 | SIB PBSCT | FA-BCNUMel/RIT | N | NA | None |
| 721/AML | 37/M | 25/09/03 | SIB PBSCT | FA-BCNUMel/RIT | N | NA | None |
| 291/AML Cr2 | 62/M | 06/02/03 | MUD PBSCT | FAra-Bu | N | NA | None |
| 292/AML Cr1 | 51/F | 07/02/03 | MUD PBSCT | RIT-Bu-CY | Y, skin III intestine IV | +32 | VOD +9/ARF+13 |
| 293/ALL Cr2 | 24/M | 11/02/03 | SIB PBSCT | TBI-VP16 | Y, skin; intestine IV | +15 | None |
| 294/AML Cr1 | 40/F | 10/02/03 | SIB PBSCT | TBI-CY | N | NA | None |
| 297/AML 1.R | 52/M | 01/03/03 | MUD PBSCT | Bu-CY | N | NA | VOD, relapse day +77 |
| 312/AML Cr2 | 52/F | 12/03/03 | SIB PBSCT | RIT-Bu-CY | Y, skin intestine II | +49 | D+14−+49; FUO |
| 313/AML Cr2 | 59/F | 07/03/03 | MUD PBSCT | RIT-Bu-CY | N | NA | FUO + 12; CMV +46 |
| 314/AML Cr1 | 22/F | 21/03/03 | SIB PBSCT | RIT-Bu-CY | N | NA | None |
| 315/MM PR | 44/F | 01/04/03 | MUD PBSCT | FAra/Mel | Y, grade II skin | +13 | None |
| 316/AML Cr1 | 52/F | 24/03/03 | SIB PBSCT | TBI-CY | N | NA | Sepsis day +6 |
| 317/CML CP1 | 42/F | 1/04/03 | MM PBSCT | TBI-CY | Y, grade II skin | +28 | CMV-R day +28 |
| 318/AML Cr2 | 45/F | 14/03/03 | MUD PBSCT | RIT/FAra/Mel | N | NA | FUO day +6 |
| 481/ALL Cr3 | 56/F | 7/04/03 | MUD BMT | TBI-CY | N | NA | CMV-R day +15 |
| 483/AML Cr1 | 38/F | 14/04/03 | SIB PBSCT | TBI-CY | N | NA | CMV-R day +14 |
| 484/AML Cr2 | 44/M | 24/04/03 | MUD PBSCT | Bu-CY | Y, grade III skin | +19 | None |
| 485/AML Cr2 | 19/M | 11/04/03 | MUD PBSCT | TBI-CY | N | NA | None |
| 486/AML Cr2 | 49/M | 07/05/03 | SIB PBSCT | Bu-CY | Y, grade III intestine | +85 | None |
| 910/MDS | 41/M | 18/07/03 | SIB PBSCT | Bu-CY | Y, grade II | +22 | ARF day +1 |
| 605/AML Cr1 | 35/F | 26/06/03 | Auto | Bu-CY | NA | NA | None |
| 1085/MM PR | 57/M | 05/12/03 | Auto | HD-Mel | NA | NA | None |
| 1087/NHL PR | 47/M | 06/12/03 | Auto | BEAM | NA | NA | None |
| 1088/NHL Cr2 | 63/F | 02/12/03 | Auto | BEAM | NA | NA | None |
| 1139/NHL PR | 63/F | 21/11/03 | Auto | BEAM | NA | NA | None |
Patient no./disease . | Age, y/sex . | Transplantation date, d/mo/y . | HSCT . | Conditioning . | GVHD . | Day after HSCT . | Other complications . |
|---|---|---|---|---|---|---|---|
| 1123/AML 1.R | 61/M | 19/06/03 | MUD PBSCT | FLAMSA | Y, grade II skin | +14 | None |
| 1124/AML refr. | 60/M | 05/09/03 | h-PBSC/BMT | FLAMSA | Y, grade II skin | +28 | Fever day −5/+6 |
| 1125/ALL Cr2 | 54/M | 11/09/03 | MUD PBSCT | FLAMSA | Y, grades I, II skin | +13 | Fever day −5/+1 |
| 1127/AML 1.R | 44/F | 15/11/03 | MUD PBSCT | FLAMSA | Y, grade II skin | +20 | None |
| 1128/AML 1.R | 36/M | 13/02/03 | h-PBSC/BMT | FLAMSA | N | NA | None |
| 1129/AML Cr1 | 50/F | 14/10/03 | SIB PBSCT | FLAMSA | N | NA | None |
| 1130/AML Cr1 | 56/M | 22/10/03 | MUD PBSCT | FLAMSA | N | NA | None |
| 1131/AML Cr1 | 58/F | 28/10/03 | SIB PBSC | FLAMSA | Y, grade II skin | +20 | None |
| 1132/AML-refr | 54/F | 29/10/03 | MUD PBSCT | FLAMSA | N | NA | Fever day −2/5 |
| 1133/AML 1.R | 34/M | 28/11/03 | h-PBSCT | FLAMSA | N | NA | Fever day 0 |
| 711/T-NHL | 22/F | 21/05/03 | MUD BMT | TBI 8 Gy FAra CY | Y, grade II skin | +75 | Fever |
| 712/AML MDS | 60/M | 14/07/03 | MUD PBSCT | FA-BCNUMel/RIT | Y, skin liver | +35 | None |
| 713/ALL/Cr1 | 26/M | 09/07/03 | MUD PBSCT | TBI-CY | Y, grade II intestine | +57 | None |
| 714/AML | 50/F | 07/07/03 | MUD PBSCT | FA-BCNUMel/RIT | Y, skin | +26 | None |
| 717/Foll. Ly | 46/M | 27/08/03 | MUD PBSCT | TBI 8 Gy FAra CY | Y, grade III skin | +19 | None |
| 720/AML | 49/F | 17/09/03 | SIB PBSCT | FA-BCNUMel/RIT | N | NA | None |
| 721/AML | 37/M | 25/09/03 | SIB PBSCT | FA-BCNUMel/RIT | N | NA | None |
| 291/AML Cr2 | 62/M | 06/02/03 | MUD PBSCT | FAra-Bu | N | NA | None |
| 292/AML Cr1 | 51/F | 07/02/03 | MUD PBSCT | RIT-Bu-CY | Y, skin III intestine IV | +32 | VOD +9/ARF+13 |
| 293/ALL Cr2 | 24/M | 11/02/03 | SIB PBSCT | TBI-VP16 | Y, skin; intestine IV | +15 | None |
| 294/AML Cr1 | 40/F | 10/02/03 | SIB PBSCT | TBI-CY | N | NA | None |
| 297/AML 1.R | 52/M | 01/03/03 | MUD PBSCT | Bu-CY | N | NA | VOD, relapse day +77 |
| 312/AML Cr2 | 52/F | 12/03/03 | SIB PBSCT | RIT-Bu-CY | Y, skin intestine II | +49 | D+14−+49; FUO |
| 313/AML Cr2 | 59/F | 07/03/03 | MUD PBSCT | RIT-Bu-CY | N | NA | FUO + 12; CMV +46 |
| 314/AML Cr1 | 22/F | 21/03/03 | SIB PBSCT | RIT-Bu-CY | N | NA | None |
| 315/MM PR | 44/F | 01/04/03 | MUD PBSCT | FAra/Mel | Y, grade II skin | +13 | None |
| 316/AML Cr1 | 52/F | 24/03/03 | SIB PBSCT | TBI-CY | N | NA | Sepsis day +6 |
| 317/CML CP1 | 42/F | 1/04/03 | MM PBSCT | TBI-CY | Y, grade II skin | +28 | CMV-R day +28 |
| 318/AML Cr2 | 45/F | 14/03/03 | MUD PBSCT | RIT/FAra/Mel | N | NA | FUO day +6 |
| 481/ALL Cr3 | 56/F | 7/04/03 | MUD BMT | TBI-CY | N | NA | CMV-R day +15 |
| 483/AML Cr1 | 38/F | 14/04/03 | SIB PBSCT | TBI-CY | N | NA | CMV-R day +14 |
| 484/AML Cr2 | 44/M | 24/04/03 | MUD PBSCT | Bu-CY | Y, grade III skin | +19 | None |
| 485/AML Cr2 | 19/M | 11/04/03 | MUD PBSCT | TBI-CY | N | NA | None |
| 486/AML Cr2 | 49/M | 07/05/03 | SIB PBSCT | Bu-CY | Y, grade III intestine | +85 | None |
| 910/MDS | 41/M | 18/07/03 | SIB PBSCT | Bu-CY | Y, grade II | +22 | ARF day +1 |
| 605/AML Cr1 | 35/F | 26/06/03 | Auto | Bu-CY | NA | NA | None |
| 1085/MM PR | 57/M | 05/12/03 | Auto | HD-Mel | NA | NA | None |
| 1087/NHL PR | 47/M | 06/12/03 | Auto | BEAM | NA | NA | None |
| 1088/NHL Cr2 | 63/F | 02/12/03 | Auto | BEAM | NA | NA | None |
| 1139/NHL PR | 63/F | 21/11/03 | Auto | BEAM | NA | NA | None |
Patients marked with “Fever” had bacteria in the blood culture in combination with fever on the indicated days and were treated with specific antibiotics. Patients with GVHD are marked “Y” and the date of the diagnosis is given in the column “Day after HSCT.” HSCT indicates hematopoietic stem cell transplantation; MUD PBSCT, matched unrelated donor peripheral stem cells; SIB PBSCT, HLA-identical sibling donor peripheral blood stem cell transplantation; MM, mismatched unrelated donor; h-PBSC/BMT, haploidentical peripheral blood and bone marrow transplantation; Auto, autologous stem cell transplantation; FAra Cy, fludarabine + cyclophosphamid; FA-BCNUMel/RIT, fludarabin, 1.3 bis(2-chloroethyl)1-nitrosourea-carmustine, melphalan/radioimmunotherapy; VP16, etoposide; FAra-Bu, fludarabin + busulfan; HD-Mel, high-dose melphalan; BEAM, dexamethasone, carmustine [BCNU], etoposide, cytarabine, melphalan; RIT, radioimmunotherapy; TBI, total body irradiation; CMV-R, cytomegalovirus-reactivation; ARF, acute renal failure; NA, not applicable; N, no GVHD; Y, GVHD; and FUO, fever of unknown origin.