Reduction of circulating B-cell percentages in WHIM patients
. | % PBLs . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Patients . | CD19+ . | CD27−IgD+ . | CD27+IgD+ . | CD27+IgD− . | |||
| P1 | 3.8 | 3.45 | 0.19 | 0.07 | |||
| P2 | 2.4 | 2.08 | 0.07 | 0.16 | |||
| P3 | 1.8 | 1.26 | 0.18 | 0.21 | |||
| Healthy control | 7.7 ± 2.7 | 4.3 ± 1.6 | 1.6 ± 1.1 | 1.6 ± 0.6 | |||
. | % PBLs . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Patients . | CD19+ . | CD27−IgD+ . | CD27+IgD+ . | CD27+IgD− . | |||
| P1 | 3.8 | 3.45 | 0.19 | 0.07 | |||
| P2 | 2.4 | 2.08 | 0.07 | 0.16 | |||
| P3 | 1.8 | 1.26 | 0.18 | 0.21 | |||
| Healthy control | 7.7 ± 2.7 | 4.3 ± 1.6 | 1.6 ± 1.1 | 1.6 ± 0.6 | |||
Percentages of peripheral blood B cells (PBLs) are reduced in WHIM patients. The analysis shown in table is representative of 2 distinct experiments involving 9 healthy control subjects. Data are presented as mean ± standard deviation for healthy controls and as means for patients.