Table 4.

Genes down-regulated more than 4-fold in the SDF versus FDF


Gene

Symbol

Accession no.

Ratio (Log2)

SD
Cell surface receptors/ligands     
    CD36 antigen* CD36 R09416  -2.3   0.6  
    Cadherin 1 type l/e-cadherin (epithelial) CDH1 R89322  -3.6   0.5  
Transporter/signal transduction     
    xk mRNA for membrane transport protein XK H18932  -2.3   1.1  
    (pwd) gene ATP7B H84807  -2.3   0.3  
Transcription factors/cell cycle     
    Erythroid Kruppel-like factor EKLF gene* KLF1 H65733  -2.7   0.7  
Cellular component/cytoskeleton     
    β-Globin (hbb) HBB N69245  -2.6   1.1  
    γ-Globin* HBG1 H53258  -2.4   0.6  
    γ-Globin  HBG1 H93108  -2.2   1.5  
    Hemoglobin ϵ-1 HBE1 H79533  -2.1   0.9  
    Adducin β subunit 63 kDa isoform* ADD2 R19254  -2.9   1.0  
Other/unknown     
    N-acetylglucosamine-6-o-sulfotransferase (glcnac6st) CHST2 N80041  -2.3   0.9  
    Cystathionine-β-synthase (cbs) CBS N54505  -2.0   1.1  
    5-Aminolevulinate synthase 2 (alas2) ALAS2 R98713  -2.0   1.3  
    Follistatin FST R01927  -2.4   1.3  
    EST similar to lphuc1 apolipoprotein c-i precursor   AI589889  -2.1   1.4  
    Precursor of apolipoprotein ci (apo ci) APOC1 H95237  -2.2   0.9  
    Similar to ae-binding protein 2*  H93462  -2.5   0.8  
    gs3955*
 
GS3955
 
R18099
 
-2.4
 
0.6
 

Gene

Symbol

Accession no.

Ratio (Log2)

SD
Cell surface receptors/ligands     
    CD36 antigen* CD36 R09416  -2.3   0.6  
    Cadherin 1 type l/e-cadherin (epithelial) CDH1 R89322  -3.6   0.5  
Transporter/signal transduction     
    xk mRNA for membrane transport protein XK H18932  -2.3   1.1  
    (pwd) gene ATP7B H84807  -2.3   0.3  
Transcription factors/cell cycle     
    Erythroid Kruppel-like factor EKLF gene* KLF1 H65733  -2.7   0.7  
Cellular component/cytoskeleton     
    β-Globin (hbb) HBB N69245  -2.6   1.1  
    γ-Globin* HBG1 H53258  -2.4   0.6  
    γ-Globin  HBG1 H93108  -2.2   1.5  
    Hemoglobin ϵ-1 HBE1 H79533  -2.1   0.9  
    Adducin β subunit 63 kDa isoform* ADD2 R19254  -2.9   1.0  
Other/unknown     
    N-acetylglucosamine-6-o-sulfotransferase (glcnac6st) CHST2 N80041  -2.3   0.9  
    Cystathionine-β-synthase (cbs) CBS N54505  -2.0   1.1  
    5-Aminolevulinate synthase 2 (alas2) ALAS2 R98713  -2.0   1.3  
    Follistatin FST R01927  -2.4   1.3  
    EST similar to lphuc1 apolipoprotein c-i precursor   AI589889  -2.1   1.4  
    Precursor of apolipoprotein ci (apo ci) APOC1 H95237  -2.2   0.9  
    Similar to ae-binding protein 2*  H93462  -2.5   0.8  
    gs3955*
 
GS3955
 
R18099
 
-2.4
 
0.6
 

The Log2 ratios of SDF/FDF were the average values of 6 hybridizations in 3 experiments. Error estimate is given as SD. Probability of differential gene expression in relation to all high-quality signals was determined with the Student t test. Accession numbers from GenBank are provided.

*

P < .001.

P < .0001.

P < .01.

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