Table 1.

Morphologic analysis of Cb2- and EGFP-transduced murine bone marrow cells cultured for 6 days



Experiment 1

Experiment 2

Experiment 3

Immature*
Premature
Mature
Immature*
Premature
Mature
Immature*
Premature
Mature
Cb2          
G§  18   30   52   15   17   68   5   11   84  
G + CP  17   39   44   29   32   39   13   30   57  
G + CP + C2  8   11   81   9   21   70   3   10   87  
EGFP          
G§  6   11   83   17   17   66   7   6   87  
G + CP  5   16   79   13   25   62   2   15   83  
G + CP + C2
 
10
 
20
 
70
 
7
 
20
 
73
 
2
 
8
 
90
 


Experiment 1

Experiment 2

Experiment 3

Immature*
Premature
Mature
Immature*
Premature
Mature
Immature*
Premature
Mature
Cb2          
G§  18   30   52   15   17   68   5   11   84  
G + CP  17   39   44   29   32   39   13   30   57  
G + CP + C2  8   11   81   9   21   70   3   10   87  
EGFP          
G§  6   11   83   17   17   66   7   6   87  
G + CP  5   16   79   13   25   62   2   15   83  
G + CP + C2
 
10
 
20
 
70
 
7
 
20
 
73
 
2
 
8
 
90
 
*

Percentage of myeloblasts and promyelocytes.

Percentage of myelocytes and metamyelocytes.

Percentage of band and segmented neutrophils.

§

G-CSF (100 ng/mL).

G-CSF + 100 nM CP55940.

G-CSF + 100 nM CP55940 + 1 μM Cb2 inverse agonist.

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