Nonsynonymous mutations in CD11b
mRNA position . | Mutation . | Amino acid exchange, mature peptide . | Allele frequency . |
|---|---|---|---|
| 230 | CGC/CAC | Arg61His | G 0.90* |
| A 0.10* | |||
| 1029 | AGC/AGA | Ser327Arg | C 0.99 |
| A 0.01 | |||
| 1322 | ATG/ACG | Met425Thr | T 0.90 |
| C 0.10 | |||
| 1498-1499 | CAG (ins) | Gly483 Gln(ins) Arg484 | Unknown |
| 2573 | GCC/GTC | Ala842Val | C 0.68 |
| T 0.32 | |||
| 2894 | CCC/CTC | Pro949Leu | Unknown |
| 3436 | CCC/TCC | Pro1130Ser | C 0.68 |
| T 0.32 |
mRNA position . | Mutation . | Amino acid exchange, mature peptide . | Allele frequency . |
|---|---|---|---|
| 230 | CGC/CAC | Arg61His | G 0.90* |
| A 0.10* | |||
| 1029 | AGC/AGA | Ser327Arg | C 0.99 |
| A 0.01 | |||
| 1322 | ATG/ACG | Met425Thr | T 0.90 |
| C 0.10 | |||
| 1498-1499 | CAG (ins) | Gly483 Gln(ins) Arg484 | Unknown |
| 2573 | GCC/GTC | Ala842Val | C 0.68 |
| T 0.32 | |||
| 2894 | CCC/CTC | Pro949Leu | Unknown |
| 3436 | CCC/TCC | Pro1130Ser | C 0.68 |
| T 0.32 |
The public database (NCBI) was screened for nonsynonymous mutations in the coding region of CD11b. Allele frequencies are according to the single-nucleotide polymorphism database at NCBI (http://www.ncbi.nlm.nih.gov/SNP). mRNA position (underlined) applies to A in the ATG start codon (1).
This study.