Table 1.

Hematopoietic characteristics of moribund mice




WBC, × 106/mL

RBC, × 1010/mL

Spleen weight, g

CFC, × 104/femur

Spleen CFC, × 103
GFP CTL (n)   7.16 ± 2.23 (12)   1.13 ± 0.22 (12)   0.15 ± 0.06 (4)   3.47 ± 0.47 (4)   1.4 ± 0.7 (2)  
NUP98-TOP1 (n)   152 ± 210 (12)   0.75 ± 0.34 (12)   0.67 ± 0.24 (8)   72 ± 64 (7)   9.8 ± 8.9 (2)  
NT-Y723F (n)
 
120 ± 77 (3)
 
0.60 ± 0.10 (3)
 
0.74 ± 0.33 (3)
 
54 ± 66 (3)
 
ND
 



WBC, × 106/mL

RBC, × 1010/mL

Spleen weight, g

CFC, × 104/femur

Spleen CFC, × 103
GFP CTL (n)   7.16 ± 2.23 (12)   1.13 ± 0.22 (12)   0.15 ± 0.06 (4)   3.47 ± 0.47 (4)   1.4 ± 0.7 (2)  
NUP98-TOP1 (n)   152 ± 210 (12)   0.75 ± 0.34 (12)   0.67 ± 0.24 (8)   72 ± 64 (7)   9.8 ± 8.9 (2)  
NT-Y723F (n)
 
120 ± 77 (3)
 
0.60 ± 0.10 (3)
 
0.74 ± 0.33 (3)
 
54 ± 66 (3)
 
ND
 

Values indicate mean ± SD. Blood cell counts were taken between 170 and 218 days after transplantation (dpt). Other parameters were measured at time animals were killed (243-321 dpt). ND indicates not done.

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