Table 3.

OR for fetal death according to the anti-EPCR autoantibody levels




Cases/controls, n

Matched OR

95% CI

P for trend
IgM     
    Q1, fewer than 33 AUs   8/22   1   —   —  
    Q2, 33-52 AUs   25/23   3.1   1.0-9.6   —  
    Q3, 53-70 AUs   19/21   2.6   0.8-9.0   —  
    Q4, more than 70 AUs   35/21   4.4   1.4-14.3   .02  
    Above p95, more than 99 AUs   16/3   45.2   2.9-662.4   —  
IgG     
    Q1, fewer than 35 AUs   18/22   1   —   —  
    Q2, 35-49 AUs   18/23   1.3   0.3-4.9   —  
    Q3, 50-57 AUs   14/20   0.8   0.2-2.7   —  
    Q4, more than 57 AUs   37/22   2.4   0.7-8.4   .12  
    Above p95, more than 94 AUs
 
13/4
 
10.2
 
1.2-86.7
 

 



Cases/controls, n

Matched OR

95% CI

P for trend
IgM     
    Q1, fewer than 33 AUs   8/22   1   —   —  
    Q2, 33-52 AUs   25/23   3.1   1.0-9.6   —  
    Q3, 53-70 AUs   19/21   2.6   0.8-9.0   —  
    Q4, more than 70 AUs   35/21   4.4   1.4-14.3   .02  
    Above p95, more than 99 AUs   16/3   45.2   2.9-662.4   —  
IgG     
    Q1, fewer than 35 AUs   18/22   1   —   —  
    Q2, 35-49 AUs   18/23   1.3   0.3-4.9   —  
    Q3, 50-57 AUs   14/20   0.8   0.2-2.7   —  
    Q4, more than 57 AUs   37/22   2.4   0.7-8.4   .12  
    Above p95, more than 94 AUs
 
13/4
 
10.2
 
1.2-86.7
 

 

Patients and controls were stratified into quartiles according to the anti-EPCR level. OR for fetal death were calculated in the 2nd (Q2), 3rd (Q3), and 4th (Q4) quartiles, and 95th percentile (p95) compared with those in the 1st (Q1) quartile. Adjustment for variables associated with fetal death included in model 1 analysis was performed. — indicates not applicable.

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