Compartmentalization of SNO and XNO in septic RBCs
.
More than 10 kDa
.
Less than 10 kDa
.
RBC SNO
5 h
57.8 ± 10
42.2 ± 11
10 h
79.6 ± 13
14.3 ± 1
RBC XNO
5 h
13.1 ± 4
86.9 ± 4
10 h
14.3 ± 1
85.7 ± 0.8
.
More than 10 kDa
.
Less than 10 kDa
.
RBC SNO
5 h
57.8 ± 10
42.2 ± 11
10 h
79.6 ± 13
14.3 ± 1
RBC XNO
5 h
13.1 ± 4
86.9 ± 4
10 h
14.3 ± 1
85.7 ± 0.8
RBCs were fractionated into high- (more than 10 kDa) and low- (less than 10 kDa) molecular weight fractions, and SNO and XNO were measured as described in “Materials and methods.” Values represent the percentage of total within either SNO or XNO pools. Values shown are mean ± SEM (n = 3).