Immunologic features and WASP expression in lymphocyte subsets
. | III-1 . | III-2* . | III-6 . |
|---|---|---|---|
| Absolute blood counts, × 109/L | |||
| White blood cells | 13.6 | 11.2 | 11.1 |
| Lymphocytes | 6.19 | 2.24 | 3.4 |
| CD3+ T cells | 5.8 | 1.65 | 1.29 |
| WASP+ cells in lymphocyte subsets, % | |||
| Lymphocytes | 79.5 | 56.7 | 11.7 |
| CD3+ T cells | 79.6 | 79.5 | 27.6 |
| CD4+ T cells | 85.9 | 60.3 | 1.9 |
| CD8+ T cells | 69.7 | 79.4 | 64.3 |
| CD45RO-CD3+ T cells | 42.0 | 65.4 | 18.9 |
| CD45RO+CD3+ T cells | 86.0 | 87.3 | 43.0 |
| CD20+ B cells | ND | NA | ND |
| CD56+ NK cells | ND | NA | ND |
. | III-1 . | III-2* . | III-6 . |
|---|---|---|---|
| Absolute blood counts, × 109/L | |||
| White blood cells | 13.6 | 11.2 | 11.1 |
| Lymphocytes | 6.19 | 2.24 | 3.4 |
| CD3+ T cells | 5.8 | 1.65 | 1.29 |
| WASP+ cells in lymphocyte subsets, % | |||
| Lymphocytes | 79.5 | 56.7 | 11.7 |
| CD3+ T cells | 79.6 | 79.5 | 27.6 |
| CD4+ T cells | 85.9 | 60.3 | 1.9 |
| CD8+ T cells | 69.7 | 79.4 | 64.3 |
| CD45RO-CD3+ T cells | 42.0 | 65.4 | 18.9 |
| CD45RO+CD3+ T cells | 86.0 | 87.3 | 43.0 |
| CD20+ B cells | ND | NA | ND |
| CD56+ NK cells | ND | NA | ND |
ND indicates not detected; and NA, not available.
Immunophenotyping and flow cytometric analysis of WASP were performed on frozen samples.