Table 1.

Summary of rhesus LCV infections


Animal no.

SHIV infection

CD4+ T-cell nadir, cells/μL

Rhesus LCV infection

LCV seroconversion

Deceased

Days after LCV infection

Comments
Group I        
    211-98   None   ND   Oral   Yes   Yes   415   Asymptomatic, killed for +PPD  
    309-98   None   ND   Oral   Yes   No   827   Alive and well  
    141-97   None   ND   Oral   Yes   No   1177   Alive and well  
    144-97   None   ND   Oral   Yes   No   1177   Alive and well  
Group II        
    255-96   89.6P   10   Oral   No   Yes   122   PCP, calcinosis  
    166-97   89.6P   3   Oral   No   yes   138   Lymphocytic pneumonia  
    343-96   89.6P   35   Oral   NA   Yes   415   PCP, failure to thrive  
    165-97   89.6P   11   Oral   No   Yes   511   Failure to thrive  
Group IIIa        
    192-98   89.6P   67   B cells   Yes   No   700   Alive, asymptomatic  
    260-98   89.6P   121   B cells   Yes   Yes   799   Failure to thrive  
Group IIIb        
    321-98   89.6P   10   B cells   No   Yes   57   Tissue invasion, Staphylococcus sepsis  
    256-96
 
89.6P
 
4
 
B cells
 
No
 
Yes
 
155
 
LCV+ tumor
 

Animal no.

SHIV infection

CD4+ T-cell nadir, cells/μL

Rhesus LCV infection

LCV seroconversion

Deceased

Days after LCV infection

Comments
Group I        
    211-98   None   ND   Oral   Yes   Yes   415   Asymptomatic, killed for +PPD  
    309-98   None   ND   Oral   Yes   No   827   Alive and well  
    141-97   None   ND   Oral   Yes   No   1177   Alive and well  
    144-97   None   ND   Oral   Yes   No   1177   Alive and well  
Group II        
    255-96   89.6P   10   Oral   No   Yes   122   PCP, calcinosis  
    166-97   89.6P   3   Oral   No   yes   138   Lymphocytic pneumonia  
    343-96   89.6P   35   Oral   NA   Yes   415   PCP, failure to thrive  
    165-97   89.6P   11   Oral   No   Yes   511   Failure to thrive  
Group IIIa        
    192-98   89.6P   67   B cells   Yes   No   700   Alive, asymptomatic  
    260-98   89.6P   121   B cells   Yes   Yes   799   Failure to thrive  
Group IIIb        
    321-98   89.6P   10   B cells   No   Yes   57   Tissue invasion, Staphylococcus sepsis  
    256-96
 
89.6P
 
4
 
B cells
 
No
 
Yes
 
155
 
LCV+ tumor
 

ND indicates not done; PPD, purified protein derivative (of tuberculin); PCP, Pneumocystis carinii pneumonia; and NA, not applicable.

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