Indications for DLI and outcome
| . | Sibling, 16 of 24 . | VUD, 10 of 38 . |
|---|---|---|
| Indication for DLI | ||
| Cytogenetic relapse | ||
| Number | 2 | 2 |
| Response | 2 CKR | 2 CKR |
| Morphologic relapse | ||
| Number | 4 | 2 |
| Response | 4 NR | 2 NR |
| Decreasing donor chimerism | ||
| Number | 10 | 6 |
| Response | 8 full donor | 6 full donor |
| Prior GVHD | 2 (Gr 1) | 1 (Gr 1) |
| Median total CD3/kg (range) | 1.1 × 107 | 8.0 × 106 |
| (6.0 × 105 to 7.2 × 107) | (1.5 × 106 to 6.2 × 107) | |
| Median days after transplantation | 264 (127-1323) | 307 (126-1290) |
| GVHD after DLI | 2 lcGVHD | 1 ecGVHD |
| 2 Gr III | 2 Gr I | |
| 1 Gr II | 1 Gr IV |
| . | Sibling, 16 of 24 . | VUD, 10 of 38 . |
|---|---|---|
| Indication for DLI | ||
| Cytogenetic relapse | ||
| Number | 2 | 2 |
| Response | 2 CKR | 2 CKR |
| Morphologic relapse | ||
| Number | 4 | 2 |
| Response | 4 NR | 2 NR |
| Decreasing donor chimerism | ||
| Number | 10 | 6 |
| Response | 8 full donor | 6 full donor |
| Prior GVHD | 2 (Gr 1) | 1 (Gr 1) |
| Median total CD3/kg (range) | 1.1 × 107 | 8.0 × 106 |
| (6.0 × 105 to 7.2 × 107) | (1.5 × 106 to 6.2 × 107) | |
| Median days after transplantation | 264 (127-1323) | 307 (126-1290) |
| GVHD after DLI | 2 lcGVHD | 1 ecGVHD |
| 2 Gr III | 2 Gr I | |
| 1 Gr II | 1 Gr IV |
CKR indicates complete karyotypic remission; NR, no response; full donor, achieved full-donor chimerism; 1cGVHD, limited chronic graft-versus-host disease; and ecGVHD, extensive chronic graft-versus-host disease.