Table 4. Immunohistochemistry data... | American Society of Hematology

Table 4.

Immunohistochemistry data summary

Patient no. and sample	CD4	CD8	CD79a	TIA-1	CAR
1
Baseline	NC	SS	−	−	−
After 3 injections	NC	+	−	++	++
2
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	++
After 6 injections	NC	++	−	+++	+++
3
Baseline	NC	SS	−	SS	−
After 3 injections	NC	+	−	++	++
4
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	+
5
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	++
After 6 injections	NC	++	−	+++	++
6
Baseline	NC	−	−	SS	−
After 3 injections	NC	+	−	++	+
7
Baseline	NC	+	−	SS	−
After 3 injections	NC	++	−	++	++
8
Baseline	+	+	+++	SS	−
After 3 injections	+	+	++	+	+
After 6 injections	++	++	+	++	+
After 9 injections	++	++	+	++	+
9
Baseline	++	SS	++	SS	−
After 3 injections	+++	+++	+	+++	+

Patient no. and sample	CD4	CD8	CD79a	TIA-1	CAR
1
Baseline	NC	SS	−	−	−
After 3 injections	NC	+	−	++	++
2
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	++
After 6 injections	NC	++	−	+++	+++
3
Baseline	NC	SS	−	SS	−
After 3 injections	NC	+	−	++	++
4
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	+
5
Baseline	NC	+	−	+	−
After 3 injections	NC	++	−	++	++
After 6 injections	NC	++	−	+++	++
6
Baseline	NC	−	−	SS	−
After 3 injections	NC	+	−	++	+
7
Baseline	NC	+	−	SS	−
After 3 injections	NC	++	−	++	++
8
Baseline	+	+	+++	SS	−
After 3 injections	+	+	++	+	+
After 6 injections	++	++	+	++	+
After 9 injections	++	++	+	++	+
9
Baseline	++	SS	++	SS	−
After 3 injections	+++	+++	+	+++	+

NC indicates no change; SS, single cells positive; −, negative; +, 5%-35% cells positive; ++, 35%-70% cells positive; and +++, > 70% cells positive.