Summary of results for epigenetic changes on the 11q13 and 14q32 loci
. | G . | N . | U . | H . | M . | K562 . | MCF7 . | 231 . | H82 . | Pt . | LCL . | NB . | T . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D1 mRNA | + | + | + | - | - | +/- | + | + | - | + | - | - | - |
| DNA methylation | |||||||||||||
| MYEOV | - | - | +/- | - | + | - | ND | ND | ND | ND | ND | ND | ND |
| MTC | - | - | - | + | + | +/- | + | + | ND | - | + | + | + |
| P519 | - | - | - | - | + | - | + | + | ND | ND | ND | ND | ND |
| D1 promoter | - | - | - | + | + | +/- | - | - | ND | - | - | - | - |
| D1 intron 4 | - | + | - | + | + | +/- | + | + | ND | ND | ND | ND | ND |
| Histone acetylation | |||||||||||||
| MYEOV | + | + | + | ND | + | + | - | ND | - | ND | + | ND | + |
| MTC | + | + | + | ND | + | + | - | ND | - | ND | - | ND | - |
| P519 | + | + | + | ND | + | + | - | ND | - | ND | + | ND | + |
| D1 promoter | + | + | + | ND | - | + (H4) - (H3) | + | ND | - | ND | + | ND | + |
| D1 intron 4 | + | + | + | ND | + | + | + | ND | + | ND | + | ND | + |
| Eμ | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| 3′ Cα HS4 | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| 3′ Cα HS3 | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| Pol II binding | |||||||||||||
| D1 promoter | + | + | ND | - | - | - | + | ND | ND | ND | - | ND | - |
| Eμ | + | + | ND | - | + | - | - | ND | ND | ND | + | ND | - |
| 3′ Cα HS4 | + | + | ND | - | + | - | - | ND | ND | ND | - | ND | - |
| 3′ Cα HS3 | + | + | ND | - | + | - | - | ND | ND | ND | - | ND | - |
. | G . | N . | U . | H . | M . | K562 . | MCF7 . | 231 . | H82 . | Pt . | LCL . | NB . | T . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D1 mRNA | + | + | + | - | - | +/- | + | + | - | + | - | - | - |
| DNA methylation | |||||||||||||
| MYEOV | - | - | +/- | - | + | - | ND | ND | ND | ND | ND | ND | ND |
| MTC | - | - | - | + | + | +/- | + | + | ND | - | + | + | + |
| P519 | - | - | - | - | + | - | + | + | ND | ND | ND | ND | ND |
| D1 promoter | - | - | - | + | + | +/- | - | - | ND | - | - | - | - |
| D1 intron 4 | - | + | - | + | + | +/- | + | + | ND | ND | ND | ND | ND |
| Histone acetylation | |||||||||||||
| MYEOV | + | + | + | ND | + | + | - | ND | - | ND | + | ND | + |
| MTC | + | + | + | ND | + | + | - | ND | - | ND | - | ND | - |
| P519 | + | + | + | ND | + | + | - | ND | - | ND | + | ND | + |
| D1 promoter | + | + | + | ND | - | + (H4) - (H3) | + | ND | - | ND | + | ND | + |
| D1 intron 4 | + | + | + | ND | + | + | + | ND | + | ND | + | ND | + |
| Eμ | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| 3′ Cα HS4 | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| 3′ Cα HS3 | + | + | ND | ND | ND | - | - | ND | ND | ND | + | ND | + |
| Pol II binding | |||||||||||||
| D1 promoter | + | + | ND | - | - | - | + | ND | ND | ND | - | ND | - |
| Eμ | + | + | ND | - | + | - | - | ND | ND | ND | + | ND | - |
| 3′ Cα HS4 | + | + | ND | - | + | - | - | ND | ND | ND | - | ND | - |
| 3′ Cα HS3 | + | + | ND | - | + | - | - | ND | ND | ND | - | ND | - |
Expression by RT-PCR, DNA methylation detectable by Southern blot or bisulfite sequencing, or in vivo binding detectable by ChIP is denoted by + or -. DNA partial methylation or trace expression is denoted by +/-.
G indicates Granta; N, NCEB1; U, U266; H, HL60; and M, Manca.