Incidence of grade 3 or 4 side effects with imatinib mesylate therapy (n = 261)
Side effect . | No. (%) . |
---|---|
Nausea, vomiting | 0 (0) |
Diarrhea | 1 (0.4) |
Skin rashes | 6 (2) |
Fluid retention | 0 (0) |
Muscle cramps | 0 (0) |
Bone or joint aches | 3 (1) |
Liver toxicity | 6 (2) |
Others* | 9 (3) |
Granulocytopenia | |
Less than 1 × 109/L | 118 (45) |
Less than 0.5 × 109/L | 45 (17) |
Anemia | |
Less than 8 g/dL | 28 (11) |
Less than 6.5 g/dL | 9 (3) |
Thrombocytopenia | |
Less than 50 × 109/L | 53 (20) |
Less than 15 × 109/L | 6 (2) |
Side effect . | No. (%) . |
---|---|
Nausea, vomiting | 0 (0) |
Diarrhea | 1 (0.4) |
Skin rashes | 6 (2) |
Fluid retention | 0 (0) |
Muscle cramps | 0 (0) |
Bone or joint aches | 3 (1) |
Liver toxicity | 6 (2) |
Others* | 9 (3) |
Granulocytopenia | |
Less than 1 × 109/L | 118 (45) |
Less than 0.5 × 109/L | 45 (17) |
Anemia | |
Less than 8 g/dL | 28 (11) |
Less than 6.5 g/dL | 9 (3) |
Thrombocytopenia | |
Less than 50 × 109/L | 53 (20) |
Less than 15 × 109/L | 6 (2) |
One fatigue, 4 fever, 2 neurologic/depression, and 2 cardiac.