Table 2.

The bleeding severity scale in patients with VWD



Severity, by symptoms and therapy
Bleeding category
0
1
2
3
Epistaxis   Absent   < 10 episodes/y   10 episodes/y   Desmopressin or FVIII/VWF conc  
   < 10 min/episode   < 10 min/episode   
   No therapy   No therapy or local therapy   
Cutaneous bleeding   Absent   < 10 episodes/y   > 10 episodes/y   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Bleeding from minor wounds   Absent   < 10 episodes/y   > 10 episodes/y   Desmopressin or FVIII/VWF conc  
   < 5 min/episode   > 5 min/episode   
   No therapy   No therapy or local therapy   
Oral cavity bleeding   Absent   After minimal trauma only   Spontaneous   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Gastrointestinal bleeding   Absent   1 bleeding episode   > 1 bleeding episode   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Bleeding after tooth extraction   Absent   Sometimes   Always   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Bleeding after surgery   Absent   Minor bleeding   Major bleeding   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Postpartum hemorrhage   Absent   Minor bleeding   Major bleeding   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Muscle hematomas   Absent   After major trauma   After minor trauma   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   No therapy or local therapy   
Hemarthrosis   Absent   After major trauma   After minor trauma   Desmopressin or FVIII/VWF conc  
   No therapy   Local therapy   
Menorrhagia
 
Absent
 
No therapy or local therapy
 
Birth control pills
 
Desmopressin or FVIII/VWF conc
 


Severity, by symptoms and therapy
Bleeding category
0
1
2
3
Epistaxis   Absent   < 10 episodes/y   10 episodes/y   Desmopressin or FVIII/VWF conc  
   < 10 min/episode   < 10 min/episode   
   No therapy   No therapy or local therapy   
Cutaneous bleeding   Absent   < 10 episodes/y   > 10 episodes/y   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Bleeding from minor wounds   Absent   < 10 episodes/y   > 10 episodes/y   Desmopressin or FVIII/VWF conc  
   < 5 min/episode   > 5 min/episode   
   No therapy   No therapy or local therapy   
Oral cavity bleeding   Absent   After minimal trauma only   Spontaneous   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Gastrointestinal bleeding   Absent   1 bleeding episode   > 1 bleeding episode   Desmopressin or FVIII/VWF conc  
   No therapy   No therapy or local therapy   
Bleeding after tooth extraction   Absent   Sometimes   Always   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Bleeding after surgery   Absent   Minor bleeding   Major bleeding   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Postpartum hemorrhage   Absent   Minor bleeding   Major bleeding   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   Local therapy   
Muscle hematomas   Absent   After major trauma   After minor trauma   Desmopressin or FVIII/VWF conc  
   No therapy or local therapy   No therapy or local therapy   
Hemarthrosis   Absent   After major trauma   After minor trauma   Desmopressin or FVIII/VWF conc  
   No therapy   Local therapy   
Menorrhagia
 
Absent
 
No therapy or local therapy
 
Birth control pills
 
Desmopressin or FVIII/VWF conc
 

Conc indicates concentrate.

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