Table 3. Haplotype frequencies Gene and... | American Society of Hematology

Table 3.

Haplotype frequencies

Gene and haplotype	Pedigree frequency	M control frequency	P*	WNH control frequency	P†
*ITGA2*
1	0.41	0.35	.30	0.39	.89
2	0.50	0.50		0.52
3	0.09	0.15		0.09
- 92C	0.82	0.85	.66	0.88	.08
- 92G	0.18	0.15		0.12
- 52C	0.63	0.59	.63	0.65	.77
- 52T	0.37	0.41		0.35
*GP6*
a	0.82	0.90	.14	0.86	.33
b	0.18	0.10		0.14
*GPIBA*
1	0.86	0.91	.35	0.92	.02
2	0.14	0.09		0.08
- 5T	0.88	0.93	.32	0.87	.85
- 5C	0.12	0.07		0.13
*ITGB3*
1	0.86	0.79	.22	0.83	.59
2	0.14	0.21		0.17
*ITGA2B*
1	0.57	0.55	.87	0.59	.72
2	0.43	0.45		0.41
*VWF*
1	0.61	0.59	.81	0.62	.98
2	0.39	0.41		0.38
*IL6*
1	0.67	0.64	.69	0.68	.92
2	0.33	0.36		0.32
*FGB*
1	0.74	0.73	.94	0.78	.37
2	0.26	0.27		0.22
*TXA2R*
1	0.66	0.79	.06	0.75	.08
2	0.34	0.21		0.25

Gene and haplotype	Pedigree frequency	M control frequency	P*	WNH control frequency	P†
*ITGA2*
1	0.41	0.35	.30	0.39	.89
2	0.50	0.50		0.52
3	0.09	0.15		0.09
- 92C	0.82	0.85	.66	0.88	.08
- 92G	0.18	0.15		0.12
- 52C	0.63	0.59	.63	0.65	.77
- 52T	0.37	0.41		0.35
*GP6*
a	0.82	0.90	.14	0.86	.33
b	0.18	0.10		0.14
*GPIBA*
1	0.86	0.91	.35	0.92	.02
2	0.14	0.09		0.08
- 5T	0.88	0.93	.32	0.87	.85
- 5C	0.12	0.07		0.13
*ITGB3*
1	0.86	0.79	.22	0.83	.59
2	0.14	0.21		0.17
*ITGA2B*
1	0.57	0.55	.87	0.59	.72
2	0.43	0.45		0.41
*VWF*
1	0.61	0.59	.81	0.62	.98
2	0.39	0.41		0.38
*IL6*
1	0.67	0.64	.69	0.68	.92
2	0.33	0.36		0.32
*FGB*
1	0.74	0.73	.94	0.78	.37
2	0.26	0.27		0.22
*TXA2R*
1	0.66	0.79	.06	0.75	.08
2	0.34	0.21		0.25

Haplotype frequencies within the 14 pedigrees, including affected and unaffected individuals (n = 67).

M control indicates Milan controls (n = 52); WNH control, white non-Hispanic controls (n = 145).

P versus Milan controls by χ² (Sigma Stat 3.0).

P versus white non-Hispanic controls by χ² (Sigma Stat 3.0).