Univariate analysis of the most frequent genomic changes
Genomic imbalance . | No. of cases . | Median OS, mo . | P* . |
|---|---|---|---|
| Genomic changes | |||
| Yes | 51 | 20.1 | .02 |
| No | 23 | 55.0 | |
| Loss of chromosomal material | |||
| Yes | 32 | 13.3 | .001 |
| No | 42 | 49.8 | |
| Gains of chromosomal material | |||
| Yes | 48 | 23.0 | .1 |
| No | 26 | 47.5 | |
| Chromosome 1q | |||
| Gain | 23 | 29.5 | .4 |
| Normal | 51 | 33.5 | |
| Chromosome 3q | |||
| Gain | 8 | 4.7 | <.001 |
| Normal | 66 | 46.4 | |
| Chromosome 5q | |||
| Gain | 12 | 12.1 | .004 |
| Normal | 62 | 46.4 | |
| Chromosome 9q | |||
| Gain | 12 | 12.1 | .046 |
| Normal | 62 | 46.4 | |
| Chromosome 11q | |||
| Gain | 11 | 10.0 | <.001 |
| Normal | 63 | 46.4 | |
| Chromosome 13q | |||
| Loss | 20 | 15.6 | .048 |
| Normal | 54 | 47.5 |
Genomic imbalance . | No. of cases . | Median OS, mo . | P* . |
|---|---|---|---|
| Genomic changes | |||
| Yes | 51 | 20.1 | .02 |
| No | 23 | 55.0 | |
| Loss of chromosomal material | |||
| Yes | 32 | 13.3 | .001 |
| No | 42 | 49.8 | |
| Gains of chromosomal material | |||
| Yes | 48 | 23.0 | .1 |
| No | 26 | 47.5 | |
| Chromosome 1q | |||
| Gain | 23 | 29.5 | .4 |
| Normal | 51 | 33.5 | |
| Chromosome 3q | |||
| Gain | 8 | 4.7 | <.001 |
| Normal | 66 | 46.4 | |
| Chromosome 5q | |||
| Gain | 12 | 12.1 | .004 |
| Normal | 62 | 46.4 | |
| Chromosome 9q | |||
| Gain | 12 | 12.1 | .046 |
| Normal | 62 | 46.4 | |
| Chromosome 11q | |||
| Gain | 11 | 10.0 | <.001 |
| Normal | 63 | 46.4 | |
| Chromosome 13q | |||
| Loss | 20 | 15.6 | .048 |
| Normal | 54 | 47.5 |
Log-rank test.