Semiquantitative analysis of immune cells in the liver
. | No. subjects . | CD68+ . | Neutrophils . | CD4+ . | CD8+ . |
---|---|---|---|---|---|
hFIX lentivirus | 6 | 1 | 1 | 0.5 | 0.5 |
Untreated | 5 | 3 | 1 | 0.5 | 0.5 |
hFIX adenovirus | 2 | 0.75 | 1.5 | 2 | 1.5 |
. | No. subjects . | CD68+ . | Neutrophils . | CD4+ . | CD8+ . |
---|---|---|---|---|---|
hFIX lentivirus | 6 | 1 | 1 | 0.5 | 0.5 |
Untreated | 5 | 3 | 1 | 0.5 | 0.5 |
hFIX adenovirus | 2 | 0.75 | 1.5 | 2 | 1.5 |
Liver biopsies were taken from normal MF1 mice 186 days after fetal intravascular hFIX-lentivirus injection (denoted by the open squares in Figure 1C), from untreated age-matched controls, or from normal adult mice 24 hours after adult intravenous hFIX-adenovirus injection.