Table 2.

Semiquantitative analysis of immune cells in the liver




No. subjects

CD68+

Neutrophils

CD4+

CD8+
hFIX lentivirus   6   1   1   0.5   0.5  
Untreated   5   3   1   0.5   0.5  
hFIX adenovirus
 
2
 
0.75
 
1.5
 
2
 
1.5
 



No. subjects

CD68+

Neutrophils

CD4+

CD8+
hFIX lentivirus   6   1   1   0.5   0.5  
Untreated   5   3   1   0.5   0.5  
hFIX adenovirus
 
2
 
0.75
 
1.5
 
2
 
1.5
 

Liver biopsies were taken from normal MF1 mice 186 days after fetal intravascular hFIX-lentivirus injection (denoted by the open squares in Figure 1C), from untreated age-matched controls, or from normal adult mice 24 hours after adult intravenous hFIX-adenovirus injection.

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