Table 1. Protocol scheme Study phase and... | American Society of Hematology

Table 1.

Protocol scheme

Study phase and week	Vitamin K intake, μg/day
Adjustment
1	0
2	0
3	0
4	0
Phase I: vitamin K from dietary supplements
5	50
6	100
7	150
8	200
9	250
10	300
11	500
Washout phase
12	0
13	0
Phase II: vitamin K from foods (single meals)
14	1500^*
15	700^*
16	103†
17	1000‡

Study phase and week	Vitamin K intake, μg/day
Adjustment
1	0
2	0
3	0
4	0
Phase I: vitamin K from dietary supplements
5	50
6	100
7	150
8	200
9	250
10	300
11	500
Washout phase
12	0
13	0
Phase II: vitamin K from foods (single meals)
14	1500^*
15	700^*
16	103†
17	1000‡

Vitamin K intakes shown are the supplement doses that each subject received above the intakes obtained from the regular diet (≈ 55 μg/day). In each week the INR was measured 4 times (on Mondays, Tuesdays, Wednesdays, and Fridays), whereas FIIc, FVIIc, ucFII, ucOC, cOC, vitamin K, and TAG were measured twice weekly (on Mondays and Tuesdays).

K₁.

†

MK-9.

‡

MK-7.

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