St Jude/Murphy Staging System for BL
Stage . | Description . |
|---|---|
| I | A single tumor (extranodal) or a single anatomic area (nodal) with the exclusion of the mediastinum or abdomen. |
| II | A single extranodal tumor with regional node involvement. |
| Two single extranodal tumors on the same side of the diaphragm with or without regional node involvement. | |
| Primary gastrointestinal tumor with or without involvement of associated mesenteric nodes only. | |
| Two or more nodal areas on the same side of the diaphragm. | |
| IIR | Completely resected intra-abdominal disease. |
| III | Two single extranodal tumors on opposite sides of the diaphragm. |
| All primary intrathoracic tumors (mediastinal, pleural, thymic). | |
| All paraspinal or epidural tumors, regardless of other tumor sites. | |
| All extensive primary intra-abdominal disease. | |
| Two or more nodal areas on opposite sides of the diaphragm. | |
| IIIA | Localized but nonresectable intra-abdominal disease. |
| IIIB | Widespread multiorgan abdominal disease. |
| IV | Any of the above with initial CNS and/or bone marrow involvement (less than 25% involvement; greater than 25% involvement is defined as L3 ALL). |
Stage . | Description . |
|---|---|
| I | A single tumor (extranodal) or a single anatomic area (nodal) with the exclusion of the mediastinum or abdomen. |
| II | A single extranodal tumor with regional node involvement. |
| Two single extranodal tumors on the same side of the diaphragm with or without regional node involvement. | |
| Primary gastrointestinal tumor with or without involvement of associated mesenteric nodes only. | |
| Two or more nodal areas on the same side of the diaphragm. | |
| IIR | Completely resected intra-abdominal disease. |
| III | Two single extranodal tumors on opposite sides of the diaphragm. |
| All primary intrathoracic tumors (mediastinal, pleural, thymic). | |
| All paraspinal or epidural tumors, regardless of other tumor sites. | |
| All extensive primary intra-abdominal disease. | |
| Two or more nodal areas on opposite sides of the diaphragm. | |
| IIIA | Localized but nonresectable intra-abdominal disease. |
| IIIB | Widespread multiorgan abdominal disease. |
| IV | Any of the above with initial CNS and/or bone marrow involvement (less than 25% involvement; greater than 25% involvement is defined as L3 ALL). |