Table 3.

Numbers of immunogold particles for myeloperoxidase in neutrophils and MKs from the spleens of normal and GATA-1low mice





Neutrophil embedded in MK


Neutrophil
MK
Neutrophil
MK
Background
Wild-type mice aged 17 mo   11.75 ± 3.9   < 1   ND   ND   0.7 ± 0.8  
GATA-1low mice aged 10-16 mo
 
46.7 ± 21.7*
 
2.3 ± 0.5
 
14.2 ± 4.5
 
25.6 ± 19.7
 
0.3 ± 0.5
 




Neutrophil embedded in MK


Neutrophil
MK
Neutrophil
MK
Background
Wild-type mice aged 17 mo   11.75 ± 3.9   < 1   ND   ND   0.7 ± 0.8  
GATA-1low mice aged 10-16 mo
 
46.7 ± 21.7*
 
2.3 ± 0.5
 
14.2 ± 4.5
 
25.6 ± 19.7
 
0.3 ± 0.5
 

Values are expressed as numbers of gold particles per 14 μm2 and are presented as mean ± SD of 5 to 20 determinations on randomly selected cells for experimental point.

ND indicates not done because neutrophils are not detected embedded in MKs from normal mice.

*

Statistically different (P < .05) from normal neutrophils.

Statistically different (P < .05) from background.

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