Multivariate analysis of graft source and factors associated with TRM, relapse, and DFS
Outcome and variable . | Hazard ratio (95% CI) . | P . |
|---|---|---|
| TRM | ||
| Graft source | .02 | |
| Cord blood | 0.32 (0.12-0.86) | |
| Bone marrow | 1.0 | |
| HLA compatibility | < .01 | |
| 1AMM | 8.22 (2.96-22.8) | |
| Other than 1AMM | 1.0 | |
| Relapse | ||
| Graft source | .73 | |
| Cord blood | 0.76 (0.16-3.56) | |
| Bone marrow | 1.0 | |
| Disease status | < .01 | |
| High-risk disease | 22.3 (5.07-97.9) | |
| Standard risk | 1.0 | |
| Diagnosis of primary disease | < .05 | |
| Other than AML | 3.25 (1.01-10.4) | |
| AML | 1.0 | |
| DFS | ||
| Graft source | < .01 | |
| Cord blood | 0.27 (0.14-0.51) | |
| Bone marrow | 1.0 | |
| Disease status | < .01 | |
| High-risk disease | 6.15 (2.70-14.0) | |
| Standard risk | 1.0 |
Outcome and variable . | Hazard ratio (95% CI) . | P . |
|---|---|---|
| TRM | ||
| Graft source | .02 | |
| Cord blood | 0.32 (0.12-0.86) | |
| Bone marrow | 1.0 | |
| HLA compatibility | < .01 | |
| 1AMM | 8.22 (2.96-22.8) | |
| Other than 1AMM | 1.0 | |
| Relapse | ||
| Graft source | .73 | |
| Cord blood | 0.76 (0.16-3.56) | |
| Bone marrow | 1.0 | |
| Disease status | < .01 | |
| High-risk disease | 22.3 (5.07-97.9) | |
| Standard risk | 1.0 | |
| Diagnosis of primary disease | < .05 | |
| Other than AML | 3.25 (1.01-10.4) | |
| AML | 1.0 | |
| DFS | ||
| Graft source | < .01 | |
| Cord blood | 0.27 (0.14-0.51) | |
| Bone marrow | 1.0 | |
| Disease status | < .01 | |
| High-risk disease | 6.15 (2.70-14.0) | |
| Standard risk | 1.0 |
TRM indicates transplantation-related mortality; 1AMM, one antigen mismatch; and DFS, disease-free survival.