Patient and transplant characteristics
Characteristics . | No. . |
---|---|
Total patients | 88 |
Men/women | 66/22 |
Median age at transplantation, y (range) | 48 (18-73) |
Histology at diagnosis | |
Indolent/LG-NHL | 41 |
Follicular NHL | 29 |
Lymphopiasmacytoid NHL | 3 |
CLL/prolymphocytic leukemia | 9 |
MCL | 10 |
Aggressive/HG-NHL | 37 |
Peripheral T-cell NHL | 4 |
Transformed low-grade NHL | 11 |
Diffuse large B-cell lymphoma | 22 |
Previous chemotherapy regimens, median (range) | 3 (1-6) |
Previous autograft (%) | |
Total | 37 (42) |
LG-NHL | 15 (37) |
MCL | 4 (40) |
HG-NHL | 19 (51) |
Disease status at transplantation | |
LG-NHL | |
CR | 11 |
Stable PR | 29 |
Ref/prog disease | 1 |
MCL | |
CR | 4 |
Stable PR | 5 |
Ref/prog disease | 1 |
HG-NHL | |
CR | 6 |
Stable PR | 23 |
Ref/prog disease | 8 |
Donor | |
HLA-identical related | 63 |
1 antigen-mismatch related | 2 |
Matched unrelated | 17 |
1 antigen-mismatch unrelated | 6 |
Stem cell source | |
PBSC | 63 |
PBSC + BM | 1 |
BM | 24 |
CMV serostatus, donor/recipient | |
Negative/negative | 34 |
Negative/positive | 19 |
Positive/negative | 10 |
Positive/positive | 25 |
Characteristics . | No. . |
---|---|
Total patients | 88 |
Men/women | 66/22 |
Median age at transplantation, y (range) | 48 (18-73) |
Histology at diagnosis | |
Indolent/LG-NHL | 41 |
Follicular NHL | 29 |
Lymphopiasmacytoid NHL | 3 |
CLL/prolymphocytic leukemia | 9 |
MCL | 10 |
Aggressive/HG-NHL | 37 |
Peripheral T-cell NHL | 4 |
Transformed low-grade NHL | 11 |
Diffuse large B-cell lymphoma | 22 |
Previous chemotherapy regimens, median (range) | 3 (1-6) |
Previous autograft (%) | |
Total | 37 (42) |
LG-NHL | 15 (37) |
MCL | 4 (40) |
HG-NHL | 19 (51) |
Disease status at transplantation | |
LG-NHL | |
CR | 11 |
Stable PR | 29 |
Ref/prog disease | 1 |
MCL | |
CR | 4 |
Stable PR | 5 |
Ref/prog disease | 1 |
HG-NHL | |
CR | 6 |
Stable PR | 23 |
Ref/prog disease | 8 |
Donor | |
HLA-identical related | 63 |
1 antigen-mismatch related | 2 |
Matched unrelated | 17 |
1 antigen-mismatch unrelated | 6 |
Stem cell source | |
PBSC | 63 |
PBSC + BM | 1 |
BM | 24 |
CMV serostatus, donor/recipient | |
Negative/negative | 34 |
Negative/positive | 19 |
Positive/negative | 10 |
Positive/positive | 25 |
Prog/ref disease indicates progressive or refractory disease.