Table 3.

RAS mutations and other recurrent genetic alterations in MM




Cyclin D1 (%)

FGFR3/MMSET*(%)

Negative(%)
RAS mutation, n = 17   11/17 (65)   0/17 (0)   6/17 (35)  
No RAS mutation, n = 37   11/37 (30)   7/37 (19)   19/37 (51)  
P
 
.015
 
.055
 
.272
 



Cyclin D1 (%)

FGFR3/MMSET*(%)

Negative(%)
RAS mutation, n = 17   11/17 (65)   0/17 (0)   6/17 (35)  
No RAS mutation, n = 37   11/37 (30)   7/37 (19)   19/37 (51)  
P
 
.015
 
.055
 
.272
 
*

Translocation t(4;14) identified by both IGH-MMSET and FGFR3/MMSET expression (see “Patients, materials, and methods”).

PCs without a detectable cyclin D1, FGFR3, MMSET, or IGH-MMSET expression.

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