Outcome of consolidation trial
. | ICE . | . | IcE . | . | Total . | . | |||
---|---|---|---|---|---|---|---|---|---|
. | % . | 95% CI . | % . | 95% CI . | % . | 95% CI . | |||
RFS at 3 years | |||||||||
All cases | 49 | 40-59 | 46 | 37-56 | 48 | 41-55 | |||
Favorable cytogenetics | 76 | 50-91 | 69 | 43-86 | 72 | 55-85 | |||
Intermediate cytogenetics | 47 | 35-58 | 47 | 36-58 | 47 | 39-55 | |||
Adverse cytogenetics | 0 | — | 20* | 5-54 | 15* | 4-45 | |||
Unknown cytogenetics | 33 | 8-73 | 20† | 3-69 | 27 | 9-59 | |||
Survival at 3 years | |||||||||
All cases | 61 | 51-71 | 62 | 52-71 | 62 | 55-68 | |||
Favorable cytogenetics | 88 | 63-97 | 79 | 50-93 | 84 | 66-93 | |||
Intermediate cytogenetics | 59 | 47-70 | 65 | 53-75 | 62 | 53-69 | |||
Adverse cytogenetics | 33 | 4-85 | 33* | 10-70 | 35 | 13-65 | |||
Unknown cytogenetics | 33 | 8-73 | 0 | — | 23 | 6-57 |
. | ICE . | . | IcE . | . | Total . | . | |||
---|---|---|---|---|---|---|---|---|---|
. | % . | 95% CI . | % . | 95% CI . | % . | 95% CI . | |||
RFS at 3 years | |||||||||
All cases | 49 | 40-59 | 46 | 37-56 | 48 | 41-55 | |||
Favorable cytogenetics | 76 | 50-91 | 69 | 43-86 | 72 | 55-85 | |||
Intermediate cytogenetics | 47 | 35-58 | 47 | 36-58 | 47 | 39-55 | |||
Adverse cytogenetics | 0 | — | 20* | 5-54 | 15* | 4-45 | |||
Unknown cytogenetics | 33 | 8-73 | 20† | 3-69 | 27 | 9-59 | |||
Survival at 3 years | |||||||||
All cases | 61 | 51-71 | 62 | 52-71 | 62 | 55-68 | |||
Favorable cytogenetics | 88 | 63-97 | 79 | 50-93 | 84 | 66-93 | |||
Intermediate cytogenetics | 59 | 47-70 | 65 | 53-75 | 62 | 53-69 | |||
Adverse cytogenetics | 33 | 4-85 | 33* | 10-70 | 35 | 13-65 | |||
Unknown cytogenetics | 33 | 8-73 | 0 | — | 23 | 6-57 |
There were 99 patients in the ICE group, 103 in the IcE group, and 202 patients total. RFS indicates relapse-free survival; —, not applicable; and survival, measured from the time of consolidation randomization.
At 2.6 years, longest surviving patient not followed beyond this time.
At 1.9 years, longest surviving patient not followed beyond this time.