Table 1. Clinical and hematologic... | American Society of Hematology

Table 1.

Clinical and hematologic features of AD DC

Generation	UPN	Age, y	Skin/nail findings	WBC/(mm³)	ANC/(mm³)	Hemoglobin level, g/dL	MCV, fL	Platelet count, × 10³/μL
I	12	68^*	+/+	8000	NA	14.7	100†	69‡
II	1	45^*	+/+	2200	1056‡	10.6‡	117†	16‡
II	2	50	+/+	3910	1900	13.0	91	293
II	3	46	+/+	3900	2391	12.3‡	104†	140‡
II	4	41	+/+	5100	2820	12.7‡	103†	196
II	5	37	+/+	5300	2760	14.7	95†	210
II	6	30	+/+	5000	3220	12.5‡	104†	94‡
III	7	22^*	+/+	4400	2068	11.4‡	118†	38‡
III	8	18	+/+	3220	1420	14.6	99†	83‡
III	9	15	–/+	5300	2690	13.0	90	255
III	10	8	–/–	5400	2376	12.1‡	89	147‡
III	11	4	–/–	9900	5500	12.5	81	228

Generation	UPN	Age, y	Skin/nail findings	WBC/(mm³)	ANC/(mm³)	Hemoglobin level, g/dL	MCV, fL	Platelet count, × 10³/μL
I	12	68^*	+/+	8000	NA	14.7	100†	69‡
II	1	45^*	+/+	2200	1056‡	10.6‡	117†	16‡
II	2	50	+/+	3910	1900	13.0	91	293
II	3	46	+/+	3900	2391	12.3‡	104†	140‡
II	4	41	+/+	5100	2820	12.7‡	103†	196
II	5	37	+/+	5300	2760	14.7	95†	210
II	6	30	+/+	5000	3220	12.5‡	104†	94‡
III	7	22^*	+/+	4400	2068	11.4‡	118†	38‡
III	8	18	+/+	3220	1420	14.6	99†	83‡
III	9	15	–/+	5300	2690	13.0	90	255
III	10	8	–/–	5400	2376	12.1‡	89	147‡
III	11	4	–/–	9900	5500	12.5	81	228

Complete blood counts and physical examinations were performed on all subjects except UPN 12 and UPN 1, where information was extracted from medical records. Skin findings included hypopigmentation or hyperpigmentation, while nail findings included ridging and dystrophic changes. WBC indicates white blood cell count; ANC, absolute neutrophil count; and MCV, mean corpuscular volume.

Dead

†

Value greater than 2 standard deviations above age-matched population

‡

Value greater than 2 standard deviations below age-matched population

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