Anti–AVC3FIX5 IgG titers following intravenous injection of AVC3FIX5 vector
Group . | No. . | Mean IgG anti-AVC3FIX5 titer . | SD . |
---|---|---|---|
A/J males | 10 | 92 160 | 21 578 |
A/J females | 10 | 66 560 | 24 732 |
C57BL/6J males | 10 | 84 480 | 29 683 |
C57BL/6J females | 10 | 102 400 | 59 121 |
Group . | No. . | Mean IgG anti-AVC3FIX5 titer . | SD . |
---|---|---|---|
A/J males | 10 | 92 160 | 21 578 |
A/J females | 10 | 66 560 | 24 732 |
C57BL/6J males | 10 | 84 480 | 29 683 |
C57BL/6J females | 10 | 102 400 | 59 121 |
The injection contained 6.8 × 1011 vector particles/kg. Values are means of reciprocals of greatest dilutions of mouse sera required to bring net OD 492 equal to that of the plate blank. There was no statistically significant difference between A/J males and C57BL/6J males (P = .52), or for A/J females versus C57BL/6J females (P = .09).