Table 3.

Anti–AVC3FIX5 IgG titers following intravenous injection of AVC3FIX5 vector


Group

No.

Mean IgG anti-AVC3FIX5 titer

SD
A/J males   10   92 160   21 578  
A/J females   10   66 560   24 732  
C57BL/6J males   10   84 480   29 683  
C57BL/6J females
 
10
 
102 400
 
59 121
 

Group

No.

Mean IgG anti-AVC3FIX5 titer

SD
A/J males   10   92 160   21 578  
A/J females   10   66 560   24 732  
C57BL/6J males   10   84 480   29 683  
C57BL/6J females
 
10
 
102 400
 
59 121
 

The injection contained 6.8 × 1011 vector particles/kg. Values are means of reciprocals of greatest dilutions of mouse sera required to bring net OD 492 equal to that of the plate blank. There was no statistically significant difference between A/J males and C57BL/6J males (P = .52), or for A/J females versus C57BL/6J females (P = .09).

or Create an Account

Close Modal
Close Modal