Table 5. Analysis of NF-κB activation,... | American Society of Hematology

Table 5.

Analysis of NF-κB activation, WBC counts, and blast percentage in 8 patients with AML

Patient no.	IκB-α mRNA, molecules per cell			White blood cells, 10³/μL	Blasts, %
Patient no.		Medium	AS602868, 10 μM	White blood cells, 10³/μL	Blasts, %
9	400 × 10³	10	79.2	> 90
1	230 × 10³	0.3	4.3	56^*
13	158 × 10³	55	129	> 90
4	1434	168	161.8	> 90
8	813	0.3	25.6	12
2	238	0.1	19.9	64^*
12	7.3	3	22.6	38^*
3	6.8	0.1	15.2	17^*

Patient no.	IκB-α mRNA, molecules per cell			White blood cells, 10³/μL	Blasts, %
Patient no.		Medium	AS602868, 10 μM	White blood cells, 10³/μL	Blasts, %
9	400 × 10³	10	79.2	> 90
1	230 × 10³	0.3	4.3	56^*
13	158 × 10³	55	129	> 90
4	1434	168	161.8	> 90
8	813	0.3	25.6	12
2	238	0.1	19.9	64^*
12	7.3	3	22.6	38^*
3	6.8	0.1	15.2	17^*

Patients are listed according to the level of IKB-α mRNA expression, and therefore do not appear in numerical order.

CD34⁺ cells were purified by positive selection on a column using magnetic field (MACS cell isolation kit)