CD34+ cell proliferation when cultured in SCF and IFN-γ, IL-4, or IL-5 for 7 days and 56 days
Week 1 . | No. generations . | Division index . | Proliferation index . | Divided, % . |
|---|---|---|---|---|
| Untreated | 7 | 1.89 | 3.02 | 62.4 |
| IFN-γ | 8 | 1.62 | 3.66 | 44.2 |
| IL-4 | 7 | 2.59 | 3.27 | 79.2 |
| IL-5 | 7 | 2.13 | 3.02 | 70.6 |
| Weeks 2-8 | ||||
| Untreated | 19 | 5.83 | 2.49 | 95.3 |
| IFN-γ | 15 | 1.21 | 2.12 | 57.2 |
| IL-4 | 14 | 1.29 | 2.28 | 56.7 |
| IL-5 | 17 | 1.5 | 2.43 | 61.7 |
Week 1 . | No. generations . | Division index . | Proliferation index . | Divided, % . |
|---|---|---|---|---|
| Untreated | 7 | 1.89 | 3.02 | 62.4 |
| IFN-γ | 8 | 1.62 | 3.66 | 44.2 |
| IL-4 | 7 | 2.59 | 3.27 | 79.2 |
| IL-5 | 7 | 2.13 | 3.02 | 70.6 |
| Weeks 2-8 | ||||
| Untreated | 19 | 5.83 | 2.49 | 95.3 |
| IFN-γ | 15 | 1.21 | 2.12 | 57.2 |
| IL-4 | 14 | 1.29 | 2.28 | 56.7 |
| IL-5 | 17 | 1.5 | 2.43 | 61.7 |
Data presented are from 1 representative experiment (n = 5). Division index is the average number of divisions that a cell (present in the starting population) has undergone. Proliferation index is the average number of divisions cells that divided underwent. Divided percentage is the percentage of cells of the original sample that divided (assuming no cell death).