Table 3. Mean sjTREC counts, CD3 /CD4... | American Society of Hematology

Table 3.

Mean sjTREC counts, CD3⁺/CD4⁺/CD8⁺/CD19⁺/CD56⁺ cell counts, CD4/CD8 cell ratio, and chimerism before and after AHSCT

	sjTREC	CD3⁺ cells	CD4⁺ cells	CD8⁺ cells	CD19⁺ cells	CD56⁺/CD16⁺/CD3^– cells	CD4/CD8 ratio	Chimerism
Group 1
Before	31 597 ± 14 558	1392 ± 319	805 ± 214	480 ± 131	153 ± 85	85 ± 26	3.2 ± 1.7	—
1 mo	3.4 ± 2	106 ± 54	41 ± 19	57 ± 31	2 ± 2	365 ± 125	0.5 ± 0.2	100 ± 0.3
2 mo	63 ± 53	137 ± 66	67 ± 45	57 ± 23	148 ± 80	405 ± 68	0.6 ± 0.2	94 ± 3
3 mo	92 ± 54	309 ± 138	127 ± 74	171 ± 91	223 ± 84	283 ± 69	0.8 ± 0.4	90 ± 5
4 mo	255 ± 66	209 ± 38	88 ± 21	99 ± 23	119 ± 56	184 ± 57	1.9 ± 0.6	93 ± 3
5 mo	789 ± 269	305 ± 82	110 ± 26	164 ± 53	98 ± 34	239 ± 69	1.2 ± 0.2	92 ± 4
6 mo	2 113 ± 698	426 ± 72	183 ± 25	212 ± 50	221 ± 54	208 ± 37	2.0 ± 0.5	91 ± 5
7 mo	4 763 ± 1 896	540 ± 120	288 ± 44	218 ± 79	380 ± 90	344 ± 81	4.0 ± 1.4	91 ± 6
8 mo	9 182 ± 3 665	737 ± 189	254 ± 24	454 ± 162	301 ± 64	303 ± 71	1.7 ± 0.4	93 ± 4
9 mo	11 398 ± 4 115	—	—	—	—	—	—	94 ± 3
10 mo	9 915 ± 4 416	—	—	—	—	—	—	95 ± 8
11 mo	12 384 ± 4 819	—	—	—	—	—	—	93 ± 3
12 mo	14 299 ± 3 277	—	—	—	—	—	—	95 ± 11
Group 2
Before	164 ± 51	276 ± 97	146 ± 62	120 ± 41	2 ± 2	57 ± 25	1.7 ± 0.6	—
1 mo	5 ± 5	7 ± 6	7 ± 5	0 ± 0	1 ± 0.4	378 ± 108	0 ± 0	100 ± 0
2 mo	8 ± 8	74 ± 66	19 ± 17	55 ± 49	38 ± 28	201 ± 56	0.1 ± 0.1	100 ± 0
3 mo	2 ± 2	130 ± 88	55 ± 33	62 ± 45	114 ± 55	214 ± 63	0.5 ± 0.3	100 ± 0
4 mo	44 ± 26	136 ± 62	72 ± 33	63 ± 34	158 ± 81	194 ± 53	2.6 ± 1.7	100 ± 0
5 mo	137 ± 95	212 ± 33	112 ± 6	95 ± 37	309 ± 143	171 ± 41	1.5 ± 0.4	99 ± 1.2
6 mo	450 ± 326	164 ± 24	99 ± 13	55 ± 15	225 ± 38	155 ± 19	2.3 ± 0.4	99 ± 1
7 mo	144 ± 95	157 ± 64	94 ± 37	49 ± 25	159 ± 57	197 ± 47	2.0 ± 0.4	100 ± 0
8 mo	1 122 ± 689	186 ± 3	114 ± 2	54 ± 7	416 ± 123	251 ± 3	2.5 ± 0.5	100 ± 0
9 mo	53 ± 29	—	—	—	—	—	—	100 ± 0
10 mo	2 686 ± 1 834	—	—	—	—	—	—	100 ± 0
11 mo	1 370 ± 672	—	—	—	—	—	—	100 ± 0
12 mo	2 079 ± 1 239	—	—	—	—	—	—	100 ± 0

	sjTREC	CD3⁺ cells	CD4⁺ cells	CD8⁺ cells	CD19⁺ cells	CD56⁺/CD16⁺/CD3^– cells	CD4/CD8 ratio	Chimerism
Group 1
Before	31 597 ± 14 558	1392 ± 319	805 ± 214	480 ± 131	153 ± 85	85 ± 26	3.2 ± 1.7	—
1 mo	3.4 ± 2	106 ± 54	41 ± 19	57 ± 31	2 ± 2	365 ± 125	0.5 ± 0.2	100 ± 0.3
2 mo	63 ± 53	137 ± 66	67 ± 45	57 ± 23	148 ± 80	405 ± 68	0.6 ± 0.2	94 ± 3
3 mo	92 ± 54	309 ± 138	127 ± 74	171 ± 91	223 ± 84	283 ± 69	0.8 ± 0.4	90 ± 5
4 mo	255 ± 66	209 ± 38	88 ± 21	99 ± 23	119 ± 56	184 ± 57	1.9 ± 0.6	93 ± 3
5 mo	789 ± 269	305 ± 82	110 ± 26	164 ± 53	98 ± 34	239 ± 69	1.2 ± 0.2	92 ± 4
6 mo	2 113 ± 698	426 ± 72	183 ± 25	212 ± 50	221 ± 54	208 ± 37	2.0 ± 0.5	91 ± 5
7 mo	4 763 ± 1 896	540 ± 120	288 ± 44	218 ± 79	380 ± 90	344 ± 81	4.0 ± 1.4	91 ± 6
8 mo	9 182 ± 3 665	737 ± 189	254 ± 24	454 ± 162	301 ± 64	303 ± 71	1.7 ± 0.4	93 ± 4
9 mo	11 398 ± 4 115	—	—	—	—	—	—	94 ± 3
10 mo	9 915 ± 4 416	—	—	—	—	—	—	95 ± 8
11 mo	12 384 ± 4 819	—	—	—	—	—	—	93 ± 3
12 mo	14 299 ± 3 277	—	—	—	—	—	—	95 ± 11
Group 2
Before	164 ± 51	276 ± 97	146 ± 62	120 ± 41	2 ± 2	57 ± 25	1.7 ± 0.6	—
1 mo	5 ± 5	7 ± 6	7 ± 5	0 ± 0	1 ± 0.4	378 ± 108	0 ± 0	100 ± 0
2 mo	8 ± 8	74 ± 66	19 ± 17	55 ± 49	38 ± 28	201 ± 56	0.1 ± 0.1	100 ± 0
3 mo	2 ± 2	130 ± 88	55 ± 33	62 ± 45	114 ± 55	214 ± 63	0.5 ± 0.3	100 ± 0
4 mo	44 ± 26	136 ± 62	72 ± 33	63 ± 34	158 ± 81	194 ± 53	2.6 ± 1.7	100 ± 0
5 mo	137 ± 95	212 ± 33	112 ± 6	95 ± 37	309 ± 143	171 ± 41	1.5 ± 0.4	99 ± 1.2
6 mo	450 ± 326	164 ± 24	99 ± 13	55 ± 15	225 ± 38	155 ± 19	2.3 ± 0.4	99 ± 1
7 mo	144 ± 95	157 ± 64	94 ± 37	49 ± 25	159 ± 57	197 ± 47	2.0 ± 0.4	100 ± 0
8 mo	1 122 ± 689	186 ± 3	114 ± 2	54 ± 7	416 ± 123	251 ± 3	2.5 ± 0.5	100 ± 0
9 mo	53 ± 29	—	—	—	—	—	—	100 ± 0
10 mo	2 686 ± 1 834	—	—	—	—	—	—	100 ± 0
11 mo	1 370 ± 672	—	—	—	—	—	—	100 ± 0
12 mo	2 079 ± 1 239	—	—	—	—	—	—	100 ± 0

In group 1, pre-AHSCT sjTREC was more than 1200; in group 2, pre-AHSCT sjTREC was fewer than 1200. SjTREC count indicates mean copies ± SE/mL blood; cell counts, mean absolute number ± SE./μL blood; chimerism, mean percentage of donor cells ± SE; and —, not tested.

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