Table 7. Multivariate analysis of... | American Society of Hematology

Table 7.

Multivariate analysis of overall mortality for patients 20 and older

Variables	N	Relative risk (95% CI)	P
0-3 mo after transplantation^*			< .001†
Japanese	562	1.00	NA
White American	829	3.63 (2.35-5.60)	< .001‡
African American	71	7.23 (3.89-13.45)	< .001‡
Scandinavian	192	1.38 (0.69-2.76)	.99‡
Irish	95	3.26 (1.64-6.50)	.008‡
More than 3 mo after transplantation			.63†
Japanese	537	1.00	NA
White American	707	0.97 (0.78-1.20)	.99‡
African American	54	1.02 (0.57-0.85)	.99‡
Scandinavian	180	0.78 (0.56-1.09)	.99‡
Irish	81	0.83 (0.51-1.38)	.99‡
Age at transplantation, y
20-40	948	1.00	NA
Older than 40	801	1.53 (1.29-1.80)	< .001
Disease type			< .001§
CML	921	1.00	NA
ALL	268	2.26 (1.82-2.81)	< .001
AML	560	1.29 (1.07-1.55)	.008
Year of transplantation
1990-1994	919	1.00	NA
1995-1999	830	0.84 (0.71-0.99)	.037

Variables	N	Relative risk (95% CI)	P
0-3 mo after transplantation^*			< .001†
Japanese	562	1.00	NA
White American	829	3.63 (2.35-5.60)	< .001‡
African American	71	7.23 (3.89-13.45)	< .001‡
Scandinavian	192	1.38 (0.69-2.76)	.99‡
Irish	95	3.26 (1.64-6.50)	.008‡
More than 3 mo after transplantation			.63†
Japanese	537	1.00	NA
White American	707	0.97 (0.78-1.20)	.99‡
African American	54	1.02 (0.57-0.85)	.99‡
Scandinavian	180	0.78 (0.56-1.09)	.99‡
Irish	81	0.83 (0.51-1.38)	.99‡
Age at transplantation, y
20-40	948	1.00	NA
Older than 40	801	1.53 (1.29-1.80)	< .001
Disease type			< .001§
CML	921	1.00	NA
ALL	268	2.26 (1.82-2.81)	< .001
AML	560	1.29 (1.07-1.55)	.008
Year of transplantation
1990-1994	919	1.00	NA
1995-1999	830	0.84 (0.71-0.99)	.037

NA indicates not applicable.

Other significant comparisons:

Scandinavian vs white American (less than 3 mo): RR = 0.38; 95% CI, 0.21-0.69; P = .015‡
Scandinavian vs African American (less than 3 mo): RR = 0.19; 95% CI, 0.09-0.40; P < .001‡

Time-dependent covariate, such that risk for TRM varied before and 3 months after transplantation.

4 degrees of freedom test.

Adjusted for 10 multiple comparisons.

2 degrees of freedom test.