Table 1. Alphabetical listing of the... | American Society of Hematology

Table 1.

Alphabetical listing of the mRNAs and median values of cases and control subjects and their range (normalized to CDKN1A)

		Patients			Controls
Gene symbol	Descriptive name	Median	Range	Median	Range	P
B2M	Beta-2-microglobulin	NA^*	NA^*	NA^*	NA^*	NA
BMI1	BMI-1 oncogene homolog	0.84	0.09-2.18	0.76	0.00-2.41	< .001
CCL3	Chemokine (C-C motif) ligand 3	0.14	0.00-0.85	0.13	0.00-1.16	< .001
CCL4	Chemokine (C-C motif) ligand 4	1.30	0.23-^*	1.26	0.23-^*	.57
CDKN1A	Cyclin-dependent kinase inhibitor 1A	NA	NA	NA	NA	NA
GSTP1	Glutathione S-transferase	0.31	0.00-1.36	0.29	0.00-1.05	< .001
IFNG	Interferon, gamma	0.16	0.00-0.80	0.15	0.00-1.78	.21
IL10	Interleukin 10	0.00	0.00-0.73	0.00	0.00-0.45	.006
IL12A	Interleukin 12, subunit p35	3.04	0.16-^*	2.76	0.16-^*	< .001
IL12B	Interleukin 12, subunit p40	0.00	0.00-0.33	0.00	0.00-1.78	.06
IL13	Interleukin 13	0.00	0.00-0.26	0.00	0.0-0.08	.96
IL15 (1)	Interleukin 15, transcript variants 1 and 3	0.48	0.13-2.59	0.46	0.16-2.52	.014
IL15 (2)	Interleukin 15, transcript variant 2	0.00	0.00-0.26	0.00	0.00-0.08	.003
IL18	Interleukin 18	0.12	0.00-1.45	0.11	0.00-0.97	.009
IL1A	Interleukin 1, alpha	0.00	0.00-0.39	0.00	0.00-0.31	< .001
IL1B	Interleukin 1, beta	0.99	0.24-^*	0.87	0.14-^*	< .001
IL1RN	Interleukin 1 receptor antagonist	1.90	0.54-^*	1.71	0.47-^*	< .001
IL2	Interleukin 2	0.07	0.00-0.52	0.03	0.00-1.19	< .001
IL4 (1)	Interleukin 4, transcript variant 1	0.00	0.00-0.31	0.00	0.00-0.22	.79
IL4 (2)	Interleukin 4, transcript variants 1 and 2	0.03	0.00-0.46	0.00	0.00-0.51	< .001
IL6	Interleukin 6	0.00	0.00-0.24	0.00	0.00-0.28	.11
IL8	Interleukin 8	1.38	0.00-^*	1.30	0.00-^*	.06
LTA	Lymphotoxin alpha (Tumor necrosis factor, beta)	0.25	0.00-1.08	0.23	0.00-0.82	< .001
MCP-1	Monocyte chemotactic protein, 1	0.00	0.00-8.22	0.14	0.00-0.70	.31
MCP-2	Monocyte chemotactic protein, 2	0.00	0.00-10.36	0.00	0.00-0.66	.07
MIF	Macrophage migration inhibitory factor	0.91	0.00-3.95	0.75	0.00-3.98	< .001
MYC	v-myc oncogene homolog	1.41	0.43-^*	1.25	0.28-^*	< .001
NFKB1	nuclear factor kappa-B, subunit 1	1.12	0.43-^*	1.02	0.19-^*	< .001
NFKB2	nuclear factor kappa-B, subunit 2	0.00	0.00-0.29	0.00	0.00-0.20	.049
NFKBIA	nuclear factor kappa-B inhibitor, alpha	2.98	0.65-^*	2.66	0.55-^*	< .001
PARN	Polyadenylate-specific ribonuclease	2.27	0.71-^*	2.34	0.67-^*	.41
PDE4B	Phosphodiesterase 4B, cAMP-specific	2.23	0.54-^*	2.12	0.58-^*	< .001
PDGFB	Platelet-derived growth factor, beta polypeptide	0.15	0.00-0.65	0.13	0.00-0.75	.002
PI9	proteinase inhibitor 9, ovalbumin type	1.81	0.24-^*	1.58	0.00-^*	< .001
PTP4A2	Protein-tyrosine phosphatase, type 4A, 2	NA^*	NA^*	NA^*	NA^*	NA
PTPN1	Protein-tyrosine phosphatase, nonreceptor-type, 1	0.24	0.00-0.63	0.21	0.00-0.79	< .001
TF	Tissue factor	0.00	0.00-0.13	0.00	0.00-0.07	.54
THBS1	Thrombospondin 1	0.29	0.00-1.47	0.30	0.00-1.40	.75
TNF	Tumor necrosis factor, alpha	0.00	0.00-0.32	0.00	0.00-0.21	.014
TNFRSF1A	Tumor necrosis factor receptor superfamily, 1A	2.77	1.02-^*	2.57	0.77-^*	< .001

		Patients			Controls
Gene symbol	Descriptive name	Median	Range	Median	Range	P
B2M	Beta-2-microglobulin	NA^*	NA^*	NA^*	NA^*	NA
BMI1	BMI-1 oncogene homolog	0.84	0.09-2.18	0.76	0.00-2.41	< .001
CCL3	Chemokine (C-C motif) ligand 3	0.14	0.00-0.85	0.13	0.00-1.16	< .001
CCL4	Chemokine (C-C motif) ligand 4	1.30	0.23-^*	1.26	0.23-^*	.57
CDKN1A	Cyclin-dependent kinase inhibitor 1A	NA	NA	NA	NA	NA
GSTP1	Glutathione S-transferase	0.31	0.00-1.36	0.29	0.00-1.05	< .001
IFNG	Interferon, gamma	0.16	0.00-0.80	0.15	0.00-1.78	.21
IL10	Interleukin 10	0.00	0.00-0.73	0.00	0.00-0.45	.006
IL12A	Interleukin 12, subunit p35	3.04	0.16-^*	2.76	0.16-^*	< .001
IL12B	Interleukin 12, subunit p40	0.00	0.00-0.33	0.00	0.00-1.78	.06
IL13	Interleukin 13	0.00	0.00-0.26	0.00	0.0-0.08	.96
IL15 (1)	Interleukin 15, transcript variants 1 and 3	0.48	0.13-2.59	0.46	0.16-2.52	.014
IL15 (2)	Interleukin 15, transcript variant 2	0.00	0.00-0.26	0.00	0.00-0.08	.003
IL18	Interleukin 18	0.12	0.00-1.45	0.11	0.00-0.97	.009
IL1A	Interleukin 1, alpha	0.00	0.00-0.39	0.00	0.00-0.31	< .001
IL1B	Interleukin 1, beta	0.99	0.24-^*	0.87	0.14-^*	< .001
IL1RN	Interleukin 1 receptor antagonist	1.90	0.54-^*	1.71	0.47-^*	< .001
IL2	Interleukin 2	0.07	0.00-0.52	0.03	0.00-1.19	< .001
IL4 (1)	Interleukin 4, transcript variant 1	0.00	0.00-0.31	0.00	0.00-0.22	.79
IL4 (2)	Interleukin 4, transcript variants 1 and 2	0.03	0.00-0.46	0.00	0.00-0.51	< .001
IL6	Interleukin 6	0.00	0.00-0.24	0.00	0.00-0.28	.11
IL8	Interleukin 8	1.38	0.00-^*	1.30	0.00-^*	.06
LTA	Lymphotoxin alpha (Tumor necrosis factor, beta)	0.25	0.00-1.08	0.23	0.00-0.82	< .001
MCP-1	Monocyte chemotactic protein, 1	0.00	0.00-8.22	0.14	0.00-0.70	.31
MCP-2	Monocyte chemotactic protein, 2	0.00	0.00-10.36	0.00	0.00-0.66	.07
MIF	Macrophage migration inhibitory factor	0.91	0.00-3.95	0.75	0.00-3.98	< .001
MYC	v-myc oncogene homolog	1.41	0.43-^*	1.25	0.28-^*	< .001
NFKB1	nuclear factor kappa-B, subunit 1	1.12	0.43-^*	1.02	0.19-^*	< .001
NFKB2	nuclear factor kappa-B, subunit 2	0.00	0.00-0.29	0.00	0.00-0.20	.049
NFKBIA	nuclear factor kappa-B inhibitor, alpha	2.98	0.65-^*	2.66	0.55-^*	< .001
PARN	Polyadenylate-specific ribonuclease	2.27	0.71-^*	2.34	0.67-^*	.41
PDE4B	Phosphodiesterase 4B, cAMP-specific	2.23	0.54-^*	2.12	0.58-^*	< .001
PDGFB	Platelet-derived growth factor, beta polypeptide	0.15	0.00-0.65	0.13	0.00-0.75	.002
PI9	proteinase inhibitor 9, ovalbumin type	1.81	0.24-^*	1.58	0.00-^*	< .001
PTP4A2	Protein-tyrosine phosphatase, type 4A, 2	NA^*	NA^*	NA^*	NA^*	NA
PTPN1	Protein-tyrosine phosphatase, nonreceptor-type, 1	0.24	0.00-0.63	0.21	0.00-0.79	< .001
TF	Tissue factor	0.00	0.00-0.13	0.00	0.00-0.07	.54
THBS1	Thrombospondin 1	0.29	0.00-1.47	0.30	0.00-1.40	.75
TNF	Tumor necrosis factor, alpha	0.00	0.00-0.32	0.00	0.00-0.21	.014
TNFRSF1A	Tumor necrosis factor receptor superfamily, 1A	2.77	1.02-^*	2.57	0.77-^*	< .001

P values are according to the (2-tailed) Mann-Whitney test.

mRNA levels above the detection limit.

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