Odds ratios with increasing quartiles of mRNA levels for a selection of markers
Inflammatory marker . | Quartile . | Patients N = 524 . | Controls N = 628 . | Crude OR . | Adjusted OR* . |
|---|---|---|---|---|---|
| MIF | 1 | 57 | 157 | 1 | 1 |
| 2 | 131 | 157 | 2.3 (1.6-3.4) | 2.1 (1.4-3.2) | |
| 3 | 143 | 157 | 2.5 (1.7-3.7) | 2.4 (1.6-3.6) | |
| 4 | 193 | 157 | 3.4 (2.3-4.9) | 3.0 (2.0-4.4) | |
| PI9 | 1 | 78 | 157 | 1 | 1 |
| 2 | 106 | 157 | 1.4 (1.0-2.0) | 1.4 (1.0-2.1) | |
| 3 | 145 | 157 | 1.9 (1.3-2.6) | 1.8 (1.2-2.6) | |
| 4 | 195 | 157 | 2.5 (1.8-3.5) | 2.6 (1.8-3.8) | |
| PTPN1 | 1 | 73 | 157 | 1 | 1 |
| 2 | 122 | 157 | 1.7 (1.2-2.4) | 1.7 (1.1-2.4) | |
| 3 | 159 | 157 | 2.2 (1.5-3.2) | 2.0 (1.4-2.9) | |
| 4 | 170 | 157 | 2.3 (1.6-3.3) | 2.2 (1.5-3.2) | |
| PDGFB | 1 | 98 | 157 | 1 | 1 |
| 2 | 124 | 157 | 1.3 (0.9-1.8) | 1.3 (0.9-1.9) | |
| 3 | 146 | 157 | 1.5 (1.1-2.1) | 1.5 (1.0-2.1) | |
| 4 | 156 | 157 | 1.6 (1.1-2.2) | 1.7 (1.2-2.4) | |
| IL12A | 1 | 92 | 157 | 1 | 1 |
| 2 | 126 | 157 | 1.4 (1.0-1.9) | 1.3 (0.9-1.9) | |
| 3 | 141 | 157 | 1.5 (1.1-2.2) | 1.4 (1.0-2.1) | |
| 4 | 165 | 157 | 1.8 (1.3-2.5) | 1.7 (1.2-2.4) | |
| NFKB1 | 1 | 90 | 157 | 1 | 1 |
| 2 | 108 | 157 | 1.2 (0.8-1.7) | 1.2 (0.8-1.7) | |
| 3 | 144 | 157 | 1.6 (1.1-2.3) | 1.4 (1.0-2.1) | |
| 4 | 182 | 157 | 2.0 (1.4-2.8) | 1.7 (1.2-2.4) | |
| MYC | 1 | 91 | 157 | 1 | 1 |
| 2 | 96 | 157 | 1.0 (0.7-1.5) | 1.0 (0.7-1.4) | |
| 3 | 155 | 157 | 1.7 (1.2-2.4) | 1.5 (1.0-2.1) | |
| 4 | 182 | 157 | 2.0 (1.4-2.8) | 1.6 (1.1-2.3) | |
| LTA | 1 | 97 | 157 | 1 | 1 |
| 2 | 107 | 157 | 1.1 (0.8-1.6) | 1.0 (0.7-1.5) | |
| 3 | 157 | 157 | 1.6 (1.2-2.3) | 1.3 (0.9-1.9) | |
| 4 | 163 | 157 | 1.7 (1.2-2.3) | 1.4 (1.0-2.0) |
Inflammatory marker . | Quartile . | Patients N = 524 . | Controls N = 628 . | Crude OR . | Adjusted OR* . |
|---|---|---|---|---|---|
| MIF | 1 | 57 | 157 | 1 | 1 |
| 2 | 131 | 157 | 2.3 (1.6-3.4) | 2.1 (1.4-3.2) | |
| 3 | 143 | 157 | 2.5 (1.7-3.7) | 2.4 (1.6-3.6) | |
| 4 | 193 | 157 | 3.4 (2.3-4.9) | 3.0 (2.0-4.4) | |
| PI9 | 1 | 78 | 157 | 1 | 1 |
| 2 | 106 | 157 | 1.4 (1.0-2.0) | 1.4 (1.0-2.1) | |
| 3 | 145 | 157 | 1.9 (1.3-2.6) | 1.8 (1.2-2.6) | |
| 4 | 195 | 157 | 2.5 (1.8-3.5) | 2.6 (1.8-3.8) | |
| PTPN1 | 1 | 73 | 157 | 1 | 1 |
| 2 | 122 | 157 | 1.7 (1.2-2.4) | 1.7 (1.1-2.4) | |
| 3 | 159 | 157 | 2.2 (1.5-3.2) | 2.0 (1.4-2.9) | |
| 4 | 170 | 157 | 2.3 (1.6-3.3) | 2.2 (1.5-3.2) | |
| PDGFB | 1 | 98 | 157 | 1 | 1 |
| 2 | 124 | 157 | 1.3 (0.9-1.8) | 1.3 (0.9-1.9) | |
| 3 | 146 | 157 | 1.5 (1.1-2.1) | 1.5 (1.0-2.1) | |
| 4 | 156 | 157 | 1.6 (1.1-2.2) | 1.7 (1.2-2.4) | |
| IL12A | 1 | 92 | 157 | 1 | 1 |
| 2 | 126 | 157 | 1.4 (1.0-1.9) | 1.3 (0.9-1.9) | |
| 3 | 141 | 157 | 1.5 (1.1-2.2) | 1.4 (1.0-2.1) | |
| 4 | 165 | 157 | 1.8 (1.3-2.5) | 1.7 (1.2-2.4) | |
| NFKB1 | 1 | 90 | 157 | 1 | 1 |
| 2 | 108 | 157 | 1.2 (0.8-1.7) | 1.2 (0.8-1.7) | |
| 3 | 144 | 157 | 1.6 (1.1-2.3) | 1.4 (1.0-2.1) | |
| 4 | 182 | 157 | 2.0 (1.4-2.8) | 1.7 (1.2-2.4) | |
| MYC | 1 | 91 | 157 | 1 | 1 |
| 2 | 96 | 157 | 1.0 (0.7-1.5) | 1.0 (0.7-1.4) | |
| 3 | 155 | 157 | 1.7 (1.2-2.4) | 1.5 (1.0-2.1) | |
| 4 | 182 | 157 | 2.0 (1.4-2.8) | 1.6 (1.1-2.3) | |
| LTA | 1 | 97 | 157 | 1 | 1 |
| 2 | 107 | 157 | 1.1 (0.8-1.6) | 1.0 (0.7-1.5) | |
| 3 | 157 | 157 | 1.6 (1.2-2.3) | 1.3 (0.9-1.9) | |
| 4 | 163 | 157 | 1.7 (1.2-2.3) | 1.4 (1.0-2.0) |
95% confidence intervals are shown in parentheses. The 1st quartile is always the reference category.
Adjusted for age, smoking, use of medication for hypertension or hypercholesterolemia, diabetes, BMI, alcohol habit, and quartile of CRP.