Analysis of multilineage engraftment following transplant of STAT5ab-/- BM into Ly-5.1 hosts
. | Wild-type . | STAT5ab-/- . |
|---|---|---|
| C57BL/6 background | ||
| Gr-1+ Ly-5.2+ | 100 ± 0 | 100 ± 0.3 |
| B220+ Ly-5.2+ | 100 ± 0 | 99 ± 0.3 |
| CD4+ Ly-5.2+ | 97 ± 2 | 36 ± 3* |
| Ter119+ Ly-5.2+ | 100 ± 1 | 85 ± 4* |
| Hbd | 100 ± 0 | 100 ± 0 |
| HW80 background | ||
| Gr-1+ Ly-5.2+ | 99 ± 1 | 93 ± 8 |
| B220+ Ly-5.2+ | 100 ± 1 | 90 ± 7 |
| CD4+ Ly-5.2+ | 92 ± 2 | 39 ± 12* |
| Ter119+ Ly-5.2+ | 95 ± 2 | 74 ± 13* |
| Hbd | 100 ± 0 | 85 ± 20 |
. | Wild-type . | STAT5ab-/- . |
|---|---|---|
| C57BL/6 background | ||
| Gr-1+ Ly-5.2+ | 100 ± 0 | 100 ± 0.3 |
| B220+ Ly-5.2+ | 100 ± 0 | 99 ± 0.3 |
| CD4+ Ly-5.2+ | 97 ± 2 | 36 ± 3* |
| Ter119+ Ly-5.2+ | 100 ± 1 | 85 ± 4* |
| Hbd | 100 ± 0 | 100 ± 0 |
| HW80 background | ||
| Gr-1+ Ly-5.2+ | 99 ± 1 | 93 ± 8 |
| B220+ Ly-5.2+ | 100 ± 1 | 90 ± 7 |
| CD4+ Ly-5.2+ | 92 ± 2 | 39 ± 12* |
| Ter119+ Ly-5.2+ | 95 ± 2 | 74 ± 13* |
| Hbd | 100 ± 0 | 85 ± 20 |
Two separate transplants for each background have been combined. There were 5 HW80 recipients for each experiment and 4 C57BL/6 recipients for each experiment. The values in the wild-type and STAT5ab-/- columns represent the percentage of the total peripheral blood leukocytes staining positive for the antibodies listed in the left-hand column. For the hemoglobin analyses, these values represent the percentage of hemoglobin diffuse (Hbd) of the total packed red blood cells.
P < .007 for comparison of wild-type and STAT5ab-/-.