Data from 3 independent transfection experiments expressed as percentages of exon 16 inclusion in both uninduced and induced MELCs, HeLa, and L8 cells
. | Exon 16 inclusion, % . | . | . | . | . | ||
|---|---|---|---|---|---|---|---|
| RNA . | Experiment 1 . | Experiment 2 . | Experiment 3 . | Average, % . | SD . | ||
| MELC | |||||||
| WT | 19.4 | 20 | 16.5 | 18.6 | 1.9 | ||
| EX-1 | 10.1 | 9.8 | 9.1 | 9.7 | 0.5 | ||
| EX-2 | 3.0 | 3.0 | 2.4 | 2.8 | 0.4 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| Induced MELC | |||||||
| WT | 55.5 | 46.6 | 45.3 | 49.1 | 5.6 | ||
| EX-1 | 7.5 | 3.4 | 8.2 | 6.4 | 2.6 | ||
| EX-2 | 2.4 | 2.6 | 3.6 | 2.9 | 0.6 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| HeLa | |||||||
| WT | 81.6 | 73.9 | 84.2 | 79.9 | 5.4 | ||
| EX-1 | 53.9 | 50.8 | 58.1 | 54.3 | 3.7 | ||
| EX-2 | 23.1 | 27.1 | 30.7 | 26.9 | 3.8 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| L8 | |||||||
| WT | 96.5 | 96.8 | 95.7 | 96.3 | 0.6 | ||
| EX-1 | 82.4 | 85.4 | 81.4 | 83.1 | 2.1 | ||
| EX-2 | 42.0 | 33.7 | 42.1 | 39.3 | 4.8 | ||
| EX-3 | 7.8 | 6.0 | 7.7 | 7.2 | 1.0 | ||
. | Exon 16 inclusion, % . | . | . | . | . | ||
|---|---|---|---|---|---|---|---|
| RNA . | Experiment 1 . | Experiment 2 . | Experiment 3 . | Average, % . | SD . | ||
| MELC | |||||||
| WT | 19.4 | 20 | 16.5 | 18.6 | 1.9 | ||
| EX-1 | 10.1 | 9.8 | 9.1 | 9.7 | 0.5 | ||
| EX-2 | 3.0 | 3.0 | 2.4 | 2.8 | 0.4 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| Induced MELC | |||||||
| WT | 55.5 | 46.6 | 45.3 | 49.1 | 5.6 | ||
| EX-1 | 7.5 | 3.4 | 8.2 | 6.4 | 2.6 | ||
| EX-2 | 2.4 | 2.6 | 3.6 | 2.9 | 0.6 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| HeLa | |||||||
| WT | 81.6 | 73.9 | 84.2 | 79.9 | 5.4 | ||
| EX-1 | 53.9 | 50.8 | 58.1 | 54.3 | 3.7 | ||
| EX-2 | 23.1 | 27.1 | 30.7 | 26.9 | 3.8 | ||
| EX-3 | 0 | 0 | 0 | 0 | 0 | ||
| L8 | |||||||
| WT | 96.5 | 96.8 | 95.7 | 96.3 | 0.6 | ||
| EX-1 | 82.4 | 85.4 | 81.4 | 83.1 | 2.1 | ||
| EX-2 | 42.0 | 33.7 | 42.1 | 39.3 | 4.8 | ||
| EX-3 | 7.8 | 6.0 | 7.7 | 7.2 | 1.0 | ||