Table 3. Probe sets up-regulated in... | American Society of Hematology

Table 3.

Probe sets up-regulated in tumors from patients with a good response to CHOP

Function/probe set	Gene symbol	Gene name	P, log-rank test^*
Cell-cycle related
1945_at	CCNB1	Cyclin B1†	.020
34736_at	CCNB1	Cyclin B1†	.010
1803_at	CDC2	Cell division cycle 2, G₁ to S and G₂ to M	.004
37347_at	CKS1B	CDC28 protein kinase regulatory subunit 1B	.005
1599_at	CDKN3	Cyclin-dependent kinase inhibitor 3†‡	.005
40348_s_at	ANP32E	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E†	.005
40347_at	ANP32E	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E†	NS
32263_at	CCNB2	Cyclin B2	NS
Mitosis
40041_at	KNTC2	Kinetochore associated 2 (highly expressed in cancer, HEC)†	NS
35699_at	BUB1B	BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)†	NS
36863_at	HMMR	Hyaluronan-mediated motility receptor (RHAMM)	NS
DNA modulation
40145_at	TOP2A	Topoisomerase (DNA) II alpha 170 kDa†	NS
38065_at	HMGB2	High-mobility group box 2†	NS
Other/unknown
38116_at	KIAA0101	KIAA0101 gene product†	.004
35071_s_at	GMDS	GDP-mannose 4,6-dehydratase	NS
39056_at	PAICS	Phosphoribosylaminoimidazole carboxylase§	NS

Function/probe set	Gene symbol	Gene name	P, log-rank test^*
Cell-cycle related
1945_at	CCNB1	Cyclin B1†	.020
34736_at	CCNB1	Cyclin B1†	.010
1803_at	CDC2	Cell division cycle 2, G₁ to S and G₂ to M	.004
37347_at	CKS1B	CDC28 protein kinase regulatory subunit 1B	.005
1599_at	CDKN3	Cyclin-dependent kinase inhibitor 3†‡	.005
40348_s_at	ANP32E	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E†	.005
40347_at	ANP32E	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E†	NS
32263_at	CCNB2	Cyclin B2	NS
Mitosis
40041_at	KNTC2	Kinetochore associated 2 (highly expressed in cancer, HEC)†	NS
35699_at	BUB1B	BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)†	NS
36863_at	HMMR	Hyaluronan-mediated motility receptor (RHAMM)	NS
DNA modulation
40145_at	TOP2A	Topoisomerase (DNA) II alpha 170 kDa†	NS
38065_at	HMGB2	High-mobility group box 2†	NS
Other/unknown
38116_at	KIAA0101	KIAA0101 gene product†	.004
35071_s_at	GMDS	GDP-mannose 4,6-dehydratase	NS
39056_at	PAICS	Phosphoribosylaminoimidazole carboxylase§	NS

NS indicates not significant.

Log-rank test for cause-specific survival

Probe sets that were selected with cross-comparison; see Table 2 for details

Other name: CDK2-associated dual specificity phosphatase

Other name: phosphoribosylaminoimidazole succinocarboxamide synthetase