Table 1.

Clinical criteria for the diagnosis of ALI and TRALI16 

Insidious, acute onset of pulmonary insufficiency  
Profound hypoxemia, PaO2/FiO2 less than 300 mm Hg* 
Bilateral fluffy infiltrates consistent with pulmonary edema  
Pulmonary artery wedge pressure less than or equal to 18 mm Hg† 
No clinical evidence of left atrial hypertension
 
Insidious, acute onset of pulmonary insufficiency  
Profound hypoxemia, PaO2/FiO2 less than 300 mm Hg* 
Bilateral fluffy infiltrates consistent with pulmonary edema  
Pulmonary artery wedge pressure less than or equal to 18 mm Hg† 
No clinical evidence of left atrial hypertension
 
*

If arterial blood gas values are unavailable, pulse oximetry less than 90% meets the criterion for hypoxemia

†

Irrespective of the pulmonary end-expiratory pressure (PEEP)

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