Table 2.

Definition of TRALI

TRALI without clinical risk factors for ALI 
   New ALI temporally related to transfusion* 
   Worsening of preexisting pulmonary insufficiency temporally related to transfusion  
TRALI with clinical risk factors for ALI 
   New ALI temporally related to transfusion* 
   New ALI thought to be mechanistically related to transfusion† 
   Worsening of preexisting pulmonary insufficiency temporally related to transfusion
 
Pulmonary insufficiency satisfies the criteria for the diagnosis of ALI.16  
TRALI without clinical risk factors for ALI 
   New ALI temporally related to transfusion* 
   Worsening of preexisting pulmonary insufficiency temporally related to transfusion  
TRALI with clinical risk factors for ALI 
   New ALI temporally related to transfusion* 
   New ALI thought to be mechanistically related to transfusion† 
   Worsening of preexisting pulmonary insufficiency temporally related to transfusion
 
Pulmonary insufficiency satisfies the criteria for the diagnosis of ALI.16  
*

ALI occurred during transfusion or within 6 hours of the completion of transfusion

†

Recognition by the clinical care team that ALI is most likely caused by transfusion

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