Genes differentially expressed in HMECs after treatment with MRP8/MRP14
Functional groups . | Up-regulated . | FC . | Down-regulated . | FC . |
|---|---|---|---|---|
| Platelet aggregation | TSP-1 | 2 | ||
| Inflammation | IL-8 | 2 | Heatshock factor 2 | 2 |
| Gro-α (CXCL1) | 2 | Complement component C3 | 2 | |
| Gro-β (CXCL2) | 2 | |||
| Monocyte secretory protein | 2 | |||
| VCAM-1 | 2 | |||
| ICAM-1 | 2 | |||
| Manganese superoxide dismutase | 3 | |||
| Cytochrome b light-chain p22 | 2 | |||
| Endothelial integrity | Trad/Duet | 4 | Catenin α1 | 2 |
| Ras-related rho | 2 | Coxsackievirus and adenovirus receptor | 2 | |
| Cadherin (protocadherin β17) | 2 | |||
| Bullous pemphigoid antigen 1 | 2 | |||
| Matrilin-2 | 2 | |||
| αV-β3 integrin | 2 | |||
| Formyl peptide receptor–like 2 | 3 | |||
| TGF-β2 receptor α | 2 | |||
| Krev-1 (Rap1) | 2 |
Functional groups . | Up-regulated . | FC . | Down-regulated . | FC . |
|---|---|---|---|---|
| Platelet aggregation | TSP-1 | 2 | ||
| Inflammation | IL-8 | 2 | Heatshock factor 2 | 2 |
| Gro-α (CXCL1) | 2 | Complement component C3 | 2 | |
| Gro-β (CXCL2) | 2 | |||
| Monocyte secretory protein | 2 | |||
| VCAM-1 | 2 | |||
| ICAM-1 | 2 | |||
| Manganese superoxide dismutase | 3 | |||
| Cytochrome b light-chain p22 | 2 | |||
| Endothelial integrity | Trad/Duet | 4 | Catenin α1 | 2 |
| Ras-related rho | 2 | Coxsackievirus and adenovirus receptor | 2 | |
| Cadherin (protocadherin β17) | 2 | |||
| Bullous pemphigoid antigen 1 | 2 | |||
| Matrilin-2 | 2 | |||
| αV-β3 integrin | 2 | |||
| Formyl peptide receptor–like 2 | 3 | |||
| TGF-β2 receptor α | 2 | |||
| Krev-1 (Rap1) | 2 |
FC indicates fold change of gene expression after treatment with MRP8/MRP14.