Table 2.

Univariate survival analysis of apoptosis-related proteins


Characteristic

N

Complete remission, %

P*

5-y survival

P
Active caspase 3      
   Low, less than 5%   53   83   .001   50   .0001  
   High, more than 5%   27   38    20   
   NI   0   —    —   
c-Flip      
   Negative   45   63   .03   30   .03  
   Positive   24   83    55   
   NI   11   —    —   
Bcl-2      
   Negative, less than 50%   16   94   .008   85   .001  
   Positive, more than 50%   63   60    30   
   NI   1   —    —   
XIAP      
   Negative, less than 50%   49   69   NS   50   .02  
   Positive, more than 50%   24   67    25   
   NI
 
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Characteristic

N

Complete remission, %

P*

5-y survival

P
Active caspase 3      
   Low, less than 5%   53   83   .001   50   .0001  
   High, more than 5%   27   38    20   
   NI   0   —    —   
c-Flip      
   Negative   45   63   .03   30   .03  
   Positive   24   83    55   
   NI   11   —    —   
Bcl-2      
   Negative, less than 50%   16   94   .008   85   .001  
   Positive, more than 50%   63   60    30   
   NI   1   —    —   
XIAP      
   Negative, less than 50%   49   69   NS   50   .02  
   Positive, more than 50%   24   67    25   
   NI
 
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NI indicates not interpretable; NS, not significant.

*

As determined by the Fisher exact test

As determined by the log rank test

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